September 2023 in “Nature Communications” In this study, the researchers found that rare genetic variants make a minor contribution to male-pattern hair loss risk, identifying five significant gene associations, including novel genes, and noting a shared basis with monogenic hair loss disorders.
January 2026 in “Frontiers in Molecular Biosciences” This study identified a four-gene loop as a non-invasive biomarker that selectively activates in alopecia areata, providing a precise target for JAK inhibitor treatments.
May 2023 in “The Journal of Immunology” In this study of C3H/HeJ mice, researchers observed that alopecia areata is associated with the expansion of exhausted-memory CD8 T cells in multiple organs, with autoreactive activation not fully explained by known mechanisms, shedding light on the immunological dynamics underlying the condition.
84 citations
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March 2004 in “Veterinary Dermatology” In randomized controlled trials, this research reports that cyclosporin is as effective as glucocorticoids for treating canine atopic dermatitis and has potential benefits for other immune-mediated skin conditions in dogs.
April 2023 in “Neurology” This study examined treatments for emesis in young Alexander disease patients, finding that 95% responded positively to valproic acid, which was more effective than anti-reflux medications or cyproheptadine, though some adverse effects require monitoring.
5 citations
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February 2019 in “The New England Journal of Medicine” This article discusses the composition and function of the dermal papilla in hair follicles, focusing on its role in hair shaft generation and suggesting that cell loss in this area may contribute to hair loss.
September 2024 in “Pediatrics in Review” This case report detailed a rare diagnosis of Rapunzel syndrome, where intussusception in a young girl was caused by trichobezoars linked to undiagnosed trichotillomania and trichophagia.
September 2023 in “Deleted Journal” This study, conducted at the Surgical Outpatient Clinics of the Medical Research Institute in Alexandria, Egypt, found that post-bariatric surgery patients commonly experienced gastrointestinal and dermatological issues, fatigue, impaired physical activity, and psychological conditions like anxiety within the first year after surgery.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study observed significant hair regrowth and near-complete restoration in a 32-year-old female with Alopecia Areata (Indralupta in Ayurveda) treated over two months with a comprehensive Ayurvedic regimen, suggesting potential effectiveness of these therapies for this condition.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This case report documented that a comprehensive Ayurvedic treatment, including therapies like Vamana and Jalaukavacharana, achieved significant hair regrowth in a 32-year-old female with Indralupta (Alopecia Areata) over two months without adverse effects.
September 2025 in “BULLETIN OF STOMATOLOGY AND MAXILLOFACIAL SURGERY” In this review, researchers explored the complex mechanisms behind chemotherapy-induced side effects like nausea, fatigue, and hair loss, and discussed potential strategies using natural agents to manage these toxicities, improving understanding for targeted adjunct therapies.
January 2024 in “Frontiers in plant science” The zinc finger protein 3 in Arabidopsis thaliana reduces plant growth and root hair development.
17 citations
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January 2010 in “Acta Dermato Venereologica” This report details a case of a 43-year-old woman developing yellowish papular eruptions alongside typical acneiform skin reactions on her cheeks and chest following a switch from cetuximab to panitumumab treatment.
8 citations
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January 2022 in “BMC Biology” This study found that the gene SRD5A1, associated with methylation changes due to early-life environment, may play a role in altering reproductive phenotypes in women by delaying pubertal onset and decreasing ovarian reserve.
June 2024 in “Sohag Medical Journal” This review reports that vitamin D plays an important role in hair follicle development, with a negative correlation observed between serum vitamin D levels and female pattern hair loss, suggesting further research is needed before recommending vitamin D as a treatment.
February 2024 in “Sohag Medical Journal” This review discusses the challenges in treating alopecia areata and the potential psychological impact, noting that spontaneous hair regrowth often occurs and highlighting the consideration of psychotherapy alongside treatment options; it reports no new experimental results.
26 citations
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July 2014 in “Analytical Chemistry Research” This study presents a validated HPTLC method for simultaneously determining five BPH drugs, showing high sensitivity and selectivity for potential use in quality-control analysis.
13 citations
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November 2014 in “Pediatric emergency care” This study reports that the ingestion of a small amount of topical minoxidil by a child resulted in significant intoxication, suggesting the need for enhanced child-resistant packaging.
April 2020 in “Journal of the Endocrine Society” This case report describes a rare occurrence of giant bilateral adrenal myelolipomas in a 28-year-old female with CAH, emphasizing that large, hormonally active, or painful myelolipomas should be surgically removed.
May 1993 in “Drugs & Therapy Perspectives” Formestane is a preferred second-line treatment for advanced breast cancer in postmenopausal women because it's effective and has fewer side effects.
In this study, researchers observed that dysregulated innate lymphoid cells type 1, alongside CD8+ T cells, may contribute to the pathogenesis of alopecia areata by affecting hair follicle health.
21 citations
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June 2016 in “Genesis” This study identified a gene expression signature in mouse embryonic dermal fibroblasts that depends on Wnt/β-catenin activity, potentially influencing dermal fibroblast identity and function.
19 citations
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December 2015 in “European Journal of Human Genetics” This study found that a novel rare variant in ITGB6 may cause intellectual disability, alopecia, and dentogingival anomalies in a specific Pakistani family, highlighting a potential role for ITGB6 beyond enamel formation.
13 citations
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October 2024 in “Scientific Reports” In this study using data from young women in West Bengal, India, the researchers identified that leptin signaling impairment, insulin resistance, and specific gene mutations significantly contribute to PCOS, with obesity commonly manifesting in affected individuals.
7 citations
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July 1975 in “Acta dermato-venereologica” This case study reports a patient with Rothmund-Thomson type congenital poikiloderma, showing primarily skin changes and hair loss, along with slightly elevated lysine and cystine levels in urine.
1 citations
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July 2017 in “Pediatric emergency care” This study suggests that most pediatric minoxidil exposures reported to Texas poison centers were unintentional, typically non-serious, and often manageable at home, despite concerns about serious adverse effects.
June 2024 in “Research Square (Research Square)” This study found that among young women in West Bengal, India, co-occurring PCOS and related conditions like estrogen resistance and leptin receptor insufficiency are common, with notable genetic variations identified, including impairments in leptin signaling and insulin resistance.
This article reviews various topics including medically important plants in dermatology, supporting medicinal herbs for primary dysmenorrhea, and several drug delivery systems, without providing new clinical findings.
Vitamin D is crucial for skin health and managing skin diseases.
245 citations
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January 2018 in “Bone Research” This review discusses the role of TGF-β signaling in stem cell recruitment and tissue regeneration, indicating that abnormalities in TGF-β activation contribute to various major diseases and suggesting avenues for therapeutic intervention.