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Apple polyphenol, especially oligomeric procyanidins, can reduce fat absorption and lower blood fat levels.

Spironolactone most effective for hirsutism, but has side effects.

Eating a high-glycemic diet may worsen acne by increasing certain protein levels and expressions in the skin.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

PDI helps restore over-bleached hair's strength and structure by attaching special peptides.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

Women with congenital adrenal hyperplasia have lower fertility, but with proper treatment, they can conceive successfully.

Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

The Drug Ontology was updated to better classify drugs for hypertension, malaria, and opioid abuse, and to allow for more accurate research queries.

Akt2 protein is essential for normal cell division in early mouse embryos.

The length of CAG repeats in the androgen receptor gene is linked to ovarian reserve but does not affect how the ovaries respond to stimulation.

Biotin supplementation during isotretinoin treatment for acne may help maintain skin hydration and improve hair growth.

Finasteride and intense pulsed light effectively reduce unwanted facial hair in women, but may not be cost-effective.

Lifestyle changes and clomiphene are first-line treatments for infertility in women with PCOS, with other options available if these fail.

Effective treatments for excessive hair growth in women include creams, laser therapy, and medications, with the choice depending on individual needs and potential side effects.

Non-drug methods like diet, supplements, and aromatherapy can help manage hair loss and its emotional impact.

New therapies show promise for wound healing, but more research is needed for safe, affordable options.

Using 5-alpha reductase inhibitors may lower the risk of breast cancer in females.

Long COVID causes various long-term health issues and needs better awareness and treatment.

A new method found unlisted drugs in two popular hair serums, posing a health risk.

Higher testosterone harms sperm motility, while higher estradiol improves sperm survival.

Women with PCOS had higher SRAGE levels, possibly linked to BMI, not PCOS.

Lifestyle changes like diet and exercise are key for treating overweight women with polycystic ovary syndrome.

Using 448-kHz Capacitive-Resistive Electrothermal Therapy can help increase hair density and prevent hair loss in women.

Finasteride reduces sperm count and quality and alters hormone levels in mice.

Finasteride and low-level laser therapy are similarly effective for frontal pattern hair loss.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.