46 citations,
August 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” Phosphatidic acid may help hair grow by affecting cell growth pathways.
24 citations,
June 2013 in “Journal of neuroendocrinology” Neuroactive steroids and the enzyme 5α-reductase might be involved in the development of Tourette's syndrome.
2 citations,
January 2019 in “Annals of Dermatology” Melandrium firmum extract helps mice grow hair by blocking a hair loss enzyme and changing hair growth genes.
21 citations,
June 2005 in “Alcoholism: Clinical and Experimental Research” Finasteride reduces alcohol withdrawal severity and anxiety in mice, but may increase withdrawal severity in some cases.
1 citations,
February 2017 in “Journal of gynecology and womens health” The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.
20 citations,
January 1994 in “Archives of Biochemistry and Biophysics” Minoxidil needs specific structure to block lysyl hydroxylase; exploring alternatives may keep benefits without this effect.
1040 citations,
October 1992 in “The New England Journal of Medicine” Finasteride effectively treats BPH but may increase sexual dysfunction risk.
93 citations,
January 1996 in “Clinical Pharmacokinectics” Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.
32 citations,
January 2000 in “Skin pharmacology and physiology” Certain substances that block a specific protein help promote hair growth.
18 citations,
January 2011 in “Bioorganic & Medicinal Chemistry Letters” New hybrid compound found to effectively prevent hair loss.
14 citations,
August 2009 in “Cancer epidemiology” AHCC reduces hair loss and liver injury caused by chemotherapy in rodents.
8 citations,
October 1988 in “Clinics in Dermatology” Current research explores hair growth drugs, while future research aims for personalized treatments.
1 citations,
March 2021 in “F1000Research” Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.
506 citations,
January 2012 in “Molecular and Cellular Endocrinology” Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
136 citations,
April 2013 in “Clinical Cancer Research” The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.
101 citations,
April 1994 in “Baillière's clinical endocrinology and metabolism” 5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
33 citations,
January 2018 in “The International Journal of Developmental Biology” Cell aging can be both good and bad for tissue repair.
8 citations,
October 1989 in “International Journal of Dermatology” Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.
6 citations,
October 2017 Indian Gooseberry has potential for cancer prevention and treatment and promotes hair growth.
6 citations,
June 2013 in “British Journal of Dermatology” Intense pulsed light treatment mainly damages pigmented hair parts but spares stem cells, allowing hair to regrow.
4 citations,
January 2018 in “Cosmetics” Spin traps like PBN could protect skin from pollution and sunlight in cosmetics but need more research for safe use.
May 2022 in “Gastroenterology” Targeting NETs may help reduce fibrosis in Crohn's disease.
April 2017 in “Journal of Investigative Dermatology” Targeted siRNA therapy may be a promising treatment for KID syndrome by reducing mutant gene expression and improving cell communication.
67 citations,
May 2018 in “Journal of Ginseng Research” Red ginseng may improve immunity, fatigue, memory, blood circulation, and menopausal symptoms, and is generally safe to consume.
10 citations,
May 2012 in “PloS one” Low ERCC3 gene activity is linked to non-pigmented hair growth.
January 2022 in “Current Enzyme Inhibition” New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.
7 citations,
September 2022 in “Communications biology” Omega-6 fats in certain cells boost male hormone production.
5 citations,
October 2022 in “Cosmetics” Cell-based models help test if cosmetic ingredients really work for hair growth and skin health.
March 2023 in “Translational Andrology and Urology” 5-alpha reductase inhibitors, like finasteride and dutasteride, are used for prostate issues, hair loss, and excessive hair growth, may help with COVID-19, but can cause sexual and mental health side effects, and their use in preventing prostate cancer needs more examination.
70 citations,
February 2016 in “EMBO reports” Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.