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New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.

A specially designed molybdenum oxide nanozyme can treat and monitor acute kidney injury effectively.

CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.

Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

Blocking SCD1 in the skin with XEN103 shrinks sebaceous glands in mice.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

New tests detect finasteride and dutasteride in urine quickly and easily.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.

The method reliably profiles eicosanoids and shows epitestosterone reduces their levels, similar to common anti-inflammatory drugs.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

Probe detects finasteride with high selectivity and low detection limit.

Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Finasteride affects brain stress and enzyme activity differently in various regions, possibly helping with liver-related brain issues.

Setipiprant may reduce inflammation by blocking an enzyme called aldose reductase.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

Aspergillus niger culture creates two finasteride derivatives with enzyme-inhibiting effects.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.