May 2021 in “International journal of developmental research” Estrogens and progesterone are key in regulating melasma pigmentation.
September 2022 in “Annals of medicine and surgery” Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.
August 2022 in “IntechOpen eBooks” Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.
5 citations,
May 2018 in “Therapeutic advances in drug safety” Androgen use may increase the risk of stroke, but more research is needed.
Certain drugs can worsen hair loss in people prone to androgenetic alopecia.
151 citations,
June 2010 in “Endocrinology and metabolism clinics of North America” Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.
23 citations,
September 2021 in “Frontiers in Cellular and Infection Microbiology” Testosterone's effects on COVID-19 are unclear and need more research.
7 citations,
August 2022 in “Journal of Nanobiotechnology” Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.
September 2022 in “Dermato” Adult acne is often related to hormonal disorders, especially in women, and may need long-term treatment involving specialists.
December 2021 in “Acta Marisiensis” Insulin resistance increases the risk of developing type 2 diabetes and other health issues.
19 citations,
January 2019 in “International Journal of Trichology” Indian dermatologists recommend treating common hair loss with a balanced diet, stress reduction, mild shampoos, and sometimes minoxidil and supplements.
2 citations,
October 2022 in “Current Allergy and Asthma Reports” Biologic therapies can cause various adverse events, but allergy/immunology clinicians can manage them.
88 citations,
September 2003 in “Clinical endocrinology” Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.
July 2023 in “Dermatology and therapy” People with alopecia areata may have a higher risk of blood clots.
9 citations,
May 2021 in “Dermatologic Therapy” Possible link between androgens and COVID-19 severity; more research needed.
September 2002 in “Comprehensive Therapy” Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.
10 citations,
July 2022 in “Dermatology and Therapy” Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.
2 citations,
January 2020 in “Methods in molecular biology” Scientists created early-stage hair follicles from human skin cells, which could help treat baldness and study hair growth.
18 citations,
January 2001 in “Annual Reports in Medicinal Chemistry” Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.
27 citations,
May 2015 in “Neuropharmacology” Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.
8 citations,
October 1998 in “Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology” Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.
Antiepileptic drugs can cause cosmetic side effects and affect menstrual cycles, fertility, and bone health in women with epilepsy.
157 citations,
April 1994 in “Clinical endocrinology” Androgens can cause hair growth in some areas and hair loss on the scalp.
88 citations,
June 2009 in “Cleveland Clinic Journal of Medicine” To manage diffuse hair loss, identify the cause, improve nutrition, remove triggers, and use specific treatments like minoxidil or finasteride.
72 citations,
January 2004 in “Dermatology” Finasteride can slow hair loss and promote growth in postmenopausal women.
36 citations,
October 2016 in “Bone” A male with aromatase deficiency improved bone health with estradiol treatment.
30 citations,
November 2009 in “British Journal of Dermatology” Higher aldosterone levels link to hair loss and high blood pressure.
21 citations,
November 2010 in “Talanta” Researchers developed a reliable method to measure testosterone and epitestosterone in urine for medical and anti-doping use.
19 citations,
July 1990 in “Cleveland Clinic journal of medicine” Androgen excess disorders in women were effectively treated with spironolactone, estrogen, and dexamethasone.
15 citations,
January 2002 in “Gynecological endocrinology” Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.