research Baiting Proteins with C60
C60 fullerenes can alter protein function and may help develop new disease inhibitors.
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research Testosterone and Doping Control
The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.
research Association Between Smoking and Hair Loss: Another Opportunity for Health Education Against Smoking?
Smoking may contribute to hair loss in men.
research Severe Acute Respiratory Syndrome (SARS)
The document concludes that rapid identification, isolation, and strict infection control are crucial to manage SARS outbreaks.
research Minoxidil-Induced Hair Growth Is Mediated by Adenosine in Cultured Dermal Papilla Cells: Possible Involvement of Sulfonylurea Receptor 2B as a Target of Minoxidil
Minoxidil boosts hair growth by targeting adenosine and possibly sulfonylurea receptor 2B.
research Androgenetic Alopecia: An Autosomal Dominant Disorder
Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.
research Repurposing of Approved Cardiovascular Drugs
Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.
research Nonclassic Adrenal Hyperplasia: Clinical Features, Diagnosis, and Treatment
Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.
research A Prospective Randomized Trial Comparing Finasteride to Spironolactone in the Treatment of Hirsute Women
Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.
research Minoxidil and the Treatment of Severe Hypertension
Minoxidil lowers blood pressure effectively but may cause unwanted hair growth and other side effects.
research 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors for the Treatment of Type 2 Diabetes
Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.
research Hydrogen Peroxide Disrupts Scarless Fetal Wound Repair
Hydrogen peroxide can cause scars by changing healing processes and increasing certain protein levels.
research Post-Finasteride Syndrome and Post-SSRI Sexual Dysfunction: Two Sides of the Same Coin?
PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.
research Network-Based Drug Repositioning: Approaches, Resources, and Research Directions
The document concludes that computational methods using networks and various data can improve the process of finding new uses for existing drugs.
research Effects of PNU157706, a Dual 5α-Reductase Inhibitor, on Rat Epididymal Sperm Maturation and Fertility
PNU157706 reduced rat sperm movement and fertility without affecting offspring health.
research Leydig Cell Hyperplasia and Adenomas in Mice Treated with Finasteride, a 5α-Reductase Inhibitor: A Possible Mechanism
High doses of finasteride cause cell growth and tumors in mice.
research Thyroid Hormone Action in Epidermal Development and Homeostasis and Its Implications in the Pathophysiology of the Skin
Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.
research Dietary Isoflavone Increases Insulin-Like Growth Factor-I Production, Thereby Promoting Hair Growth in Mice
Eating isoflavone can help mice grow hair by increasing a growth factor.
research Age-Related Changes in Brain and Pituitary 5α-Reductase with Finasteride (Proscar) Treatment
Finasteride affects prostate weights and pituitary activity differently with age.
research Hormonal Trends in Patients Suffering from Long COVID Symptoms
Long COVID patients may have hormonal imbalances linked to their symptoms.
research Steroid Sulfatase Inhibitors: Therapeutic Applications and Development
Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.
research Topical Formulations Containing Finasteride: In Vitro Permeation/Penetration Study and In Vivo Pharmacokinetics in Hairless Rat
Finasteride cream helps hair growth with less side effects.
research Procyanidins Attenuate Neuropathic Pain by Suppressing Matrix Metalloproteinase-9/2
Procyanidins from grape seeds reduce nerve pain by blocking specific proteins and inflammation.
research Adipose Stem Cells From Type 2 Diabetic Mice Exhibit Therapeutic Potential In Wound Healing
Fat stem cells from diabetic mice can still help heal wounds.
research A Guide to Studying Human Dermal Adipocytes In Situ
The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.
research Antianaphylactic Activity of Alcoholic Extract of Eclipta Alba
Alcoholic extract of Eclipta alba may help treat allergies and is safe at high doses.
research Exposure of Xenopus Laevis Tadpoles to Finasteride, an Inhibitor of 5-Alpha Reductase Activity, Impairs Spermatogenesis and Alters Hypophyseal Feedback Mechanisms
Finasteride exposure harms tadpole reproduction and hormone balance.
research 7-Phloroeckol Promotes Hair Growth on Human Follicles In Vitro
7-Phloroeckol from brown algae may help hair grow.
research 5α-Reductase Inhibitors
Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.
research Finasteride, a 5α-Reductase Inhibitor, Potentiates Antinociceptive Effects of Morphine, Prevents the Development of Morphine Tolerance and Attenuates Abstinence Behavior in the Rat
Finasteride boosts morphine's pain relief, stops tolerance, and reduces withdrawal in rats.