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There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

Oxidative stress damages hair and contributes to aging, and managing it can help maintain hair health.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

Celiac disease can cause skin problems that may get better with a gluten-free diet.

Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.

Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.

Key genes are crucial for Drosophila wing development and could be insecticide targets.

Vitamin D receptor is crucial for starting hair growth after birth.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.

The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

MicroRNAs are crucial for controlling skin development and healing by regulating genes.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

Tofacitinib is somewhat effective for alopecia areata, but more research is needed on its safety and long-term effects.

Lifestyle changes and weight loss are key for treating PCOS-related metabolic issues and infertility, with various medications available for specific symptoms.

Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.

Minoxidil helps grow longer, thicker hair in bald scalps of stumptailed macaques, and early treatment is more effective.

Finasteride and minoxidil work best together for hair loss.

Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.

Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.