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Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

TGase 3 helps build hair structure by forming strong bonds between proteins.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

The mouse model suggests male pattern baldness may be due to an enzyme increasing DHT and higher androgen receptor levels in hair follicles.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.

Certain drugs that block specific enzymes can help treat prostate diseases.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

People with Mucopolysaccharidoses often have skin problems like thick skin and extra hair, and recognizing these can help diagnose and treat the condition early.

Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.

The enzyme sEH is important for hair growth and its inhibition could help treat hair loss.

DGAT1 enzyme is crucial for healthy skin and hair by regulating retinoid levels.

Longer GGN repeats in the androgen receptor gene are linked to polycystic ovary syndrome.

Overexpressing a specific enzyme in mice causes hair loss and female infertility.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

PNKP is essential for keeping adult mouse progenitor cells healthy and growing normally.

The study created a new method to test drugs that affect hormone processing in skin.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.

The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Bee venom helps hair grow and may work better than some common treatments.

A substance called compound-1 could help increase hair growth by maintaining prostaglandin levels in hair follicles.

Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.