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This study explored the structure and function of lipocalin prostaglandin D synthase, revealing its dual role in substrate catalysis and as a lipophilic ligand carrier, potentially informing future drug delivery design.

CD73 may regulate hair growth and could be targeted for hair growth treatments.

This study found that certain CYP21A2 mutations significantly reduce enzyme activity, contributing to non-classic congenital adrenal hyperplasia phenotypes, which may aid in enhancing diagnosis and treatment strategies.

This study examined uncharacterized CYP21A2 gene variants related to non-classic congenital adrenal hyperplasia and found that several mutations reduce enzyme activity, which may help improve diagnostic and treatment strategies.

This study found that selective deletion of PIKFyve kinase using a PF4 promoter in mice led to defective platelet lysosome biogenesis and a prothrombotic effect, with unexpected macrophage infiltration in multiple organs.

This study found that women with PCOS who have an exaggerated 17-hydroxyprogesterone response to buserelin exhibit more severe hyperandrogenemia, increased insulin secretion, and reduced insulin sensitivity.

This study found that overexpression of sPLA2-X in mice was associated with alopecia and hair follicle abnormalities, highlighting its potential role in hair follicle homeostasis.

This review discusses the structure and assembly of the cornified cell envelope in stratified squamous epithelial cells and various disorders leading to barrier defects, but reports no new findings.

This case report details a patient with myasthenia gravis and a malignant thymoma whose rising liver function tests, initially thought to be related to antibiotic use, were ultimately attributed to thymoma-associated multiorgan autoimmunity.

This study found that Nrf2 activation protected keratinocytes from UVB damage but also caused thickening, inflammation, and cysts, limiting its therapeutic potential for skin protection.

In this study, T3 and T4 were found to directly influence human hair follicles in vitro, enhancing keratinocyte proliferation, prolonging the hair growth phase, and affecting pigmentation.

This review discusses the mechanisms of zinc transport, its role in human health, and the effects of zinc imbalance, without reporting new results.

This review examines how epigenetic dysregulation affects adult stem cell function, noting that impacts range from minor to serious disruptions in tissue homeostasis and potential cancer development.

The researchers found that plant extracts from Papaver rhoeas L., Clitoria ternatea L., and Carthamus tinctorius L. are effective natural cosmetic dyes, offering intense and stable colors without cytotoxicity.

This review discusses the protective and stress-buffering roles of melatonin in skin functions and structures but does not present new clinical findings.

This study identified a heterozygous de novo mutation in the ODC1 gene causing a new disorder characterized by overgrowth and developmental delay, and suggests that DFMO treatment may help manage elevated ODC activity and putrescine levels.

In this study, oral administration of ginsenoside Rf from Panax ginseng promoted hair regrowth and increased hair thickness in a mouse model of androgenetic alopecia by enhancing androgen receptor degradation, highlighting its potential for cosmetic and functional food applications.

This study introduces MicrobeFDT, a tool that clusters chemically similar compounds and links them to gut microbial enzymes and toxicities, demonstrating its utility by uncovering previously unknown metabolism of the cancer drug altretamine.

In this study, Alhanshali and co-authors reported that low-dose oral minoxidil, used for treating androgenetic alopecia, may worsen hangover symptoms in some male patients, potentially due to interactions with alcohol that affect blood pressure and metabolic processes.

This article reviews the role of enzymatic processes in drug and toxin metabolism, emphasizing their impact on solubility and elimination, without presenting new clinical findings.

This review discusses recent advances in understanding gender differences in skin and their implications for dermatologic diseases, but it reports no new experimental results; ongoing research is necessary for translating these insights into clinical practice.

This study validated a method for measuring cortisol levels in hair, which may serve as a biomarker for chronic stress in both humans and various animals.

This study found that flutamide-induced liver toxicity in prostate cancer patients was very rare, occurring in only 0.18% of cases with clinical manifestations, and symptoms resolved after discontinuing the drug.

This review discusses the impact of melatonin and its metabolites on skin aging, summarizing how they may serve as "aging neutralizers" through their anti-oxidative and anti-inflammatory properties, but reports no new clinical results.

This review discusses various aspects of hair follicle biology and highlights unresolved questions and potential new research avenues, but presents no new experimental findings.

This review explores the applications of magnetized water in agriculture and medicine and notes potential benefits for human health, but it presents no new experimental findings.

This review highlights that isotretinoin effectively treats acne by addressing its pathogenic mechanisms, although managing its teratogenic risk and side effects through structured monitoring is crucial for safe use.

In this study, long-term occupational exposure to benzene in fueling workers was associated with increased skin diseases, altered blood cell counts, and elevated liver enzyme levels compared to overseers.

This chapter describes the functions and purposes of hair care cosmetics, including shampoos, hair growth promoters, and grooming products, without reporting new experimental findings.

This case report highlights a 53-year-old woman who developed acute hepatitis after taking shou-wu-pian for eight months, suggesting that Chinese herbal preparations can sometimes cause liver damage.