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New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Valproic acid treatment increases a specific acid in urine by blocking an enzyme, possibly causing skin rash and hair loss.

Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.

New treatments for excessive hair growth in women include insulin modulators and enzyme inhibitors.

Sophora flavescens extract may help hair grow by affecting growth factors and blocking a hair-related enzyme.

Topical 5-Fluorouracil can rarely cause nerve damage, especially in people with a certain genetic deficiency.

Eat a balanced diet for healthy hair; only use supplements if you have a proven nutrient deficiency.

Eating the right nutrients can improve hair health, but taking extra supplements usually doesn't help unless you have a deficiency.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.

Adult mice with CBS deficiency show minimal health issues and normal lifespan despite high homocysteine levels.

Iron supplements can restore normal hair color in cases of premature graying linked to iron deficiency.

Certain genetic variants reduce enzyme activity, contributing to non-classic congenital adrenal hyperplasia.

Certain genetic variants impair enzyme activity, contributing to non-classic congenital adrenal hyperplasia.

People with alopecia areata often have lower iron levels than healthy people.

Iron and zinc deficiencies may be treated to help female hair loss.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Low iron levels may be linked to some types of hair loss in women.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Estrogen therapy can reduce skin aging but has cancer risks.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

Children taking higher doses of valproic acid had lower biotinidase activity, which may lead to biotin deficiency, but biotin supplements could help.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Certain groups may need vitamin supplements to improve hair health and prevent other health problems.