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Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

Methotrexate is effective and well-tolerated in children for certain skin conditions but requires careful monitoring.

Hair follicle sampling is a practical method for measuring biomarkers in children with and without Fragile X syndrome.

Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.

Hair dye ingredient PPD causes cell death and aging in human hair cells by altering microRNA levels.

Researchers made stem cells from human hair follicle cells with better efficiency than from skin cells.

Using mesenchymal stem cells or their exosomes is safe for COVID-19 patients and helps improve lung healing and oxygen levels.

HA-stimulated stem cell vesicles improved hair growth in male mice with androgenetic alopecia.

Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.

Environmental factors and chemicals might affect hormone balance and contribute to common hair loss.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.

Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.

Dermal fibroblasts have adjustable roles in wound healing, with specific cells promoting regeneration or scar formation.

Bimatoprost is effective for growing longer, thicker, and darker eyelashes.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

Trichloroethylene causes skin inflammation in mice by increasing certain immune proteins.

Akebia quinata and Akebia trifoliata have many health benefits and potential medical uses.

Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.

Colchicine might help treat different skin diseases, but more research is needed to confirm its effectiveness and safe dosage.

Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.

COVID-19 can cause various skin issues, like rashes and lesions, which are more common in younger patients and can be linked to more severe complications.

Hairless protein affects hair follicle structure by regulating the Dlx3 gene.

Sox6 is important in heart and kidney health, affecting diseases like diabetes, heart disease, and high blood pressure.

EGCG may help treat alopecia areata by blocking certain immune responses and reducing specific harmful immune cells.

High mTORC1 activity slows hair growth and causes it to lose color.

Targeting a protein that blocks hair growth with microRNAs could lead to new hair loss treatments, but more research is needed.