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Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.

Plant hormones have potential in agriculture to increase food production but require more research for effective use.

Activating β-catenin in mammary cells leads to changes that cause early-stage abnormal growths similar to skin structures.

Higher minoxidil dose helps hair growth in non-responders without side effects.

Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.

Topical 5-Fluorouracil can rarely cause nerve damage, especially in people with a certain genetic deficiency.

The enzyme Rand protease works well for leather dehairing and its stability is important, with Leu75 playing a key role.

Chemotherapy and radiation therapy cause skin and hair damage by altering gene expression and signaling pathways.

Early and late matrix progenitors in hair follicles create different cell layers, with early ones forming the companion layer and later ones forming the inner root sheath and hair shaft.

Researchers improved a method to study individual cells in newborn mouse skin and found a way to assess the severity of a skin condition in humans.

The study found a link between the severity of Lichen Planopilaris seen by doctors and the details seen under a microscope, and created a new way to measure this severity.

Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Human skin can make serotonin and melatonin.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Essential oils in cosmetics can offer benefits but may cause allergies and should be used carefully.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.