23 citations
,
October 2018 in “Australasian Journal of Dermatology” This review highlights that frontal fibrosing alopecia’s increasing incidence may involve immune, genetic, hormonal, and environmental factors, yet its pathogenesis remains complex and not fully understood.
22 citations
,
September 2019 in “Trends in Immunology” This paper proposes that acne vulgaris is a transient inflammatory response during adolescence due to changes in facial skin's microbiota and sebum environment rather than a stable skin condition.
August 2023 in “Physician's journal of medicine” This review provides a detailed overview of Hashimoto thyroiditis, discussing its epidemiology, risk factors, genetic and environmental contributors, clinical presentations, diagnostic methods, and treatment options, emphasizing the importance of personalized treatment plans due to varied causes and symptoms.
1 citations
,
February 2025 in “Medicina” This study examined genetic risk factors for alopecia areata in the Jordanian population but found no significant association between the 21 targeted risk loci and the condition, emphasizing variability in genetic predisposition across ethnic groups and potential non-genetic triggers.
6 citations
,
January 2018 in “International Journal of Trichology” This report describes the first known case of frontal fibrosing alopecia in a genetically unrelated couple, suggesting the potential role of environmental factors in its development.
October 2024 in “International Journal of Research in Orthopaedics” This study found that adolescents carrying the HLA-B27 antigen who engaged in intense physical activity were more likely to develop ankylosing spondylitis, although not all predisposed individuals were affected, indicating other genetic and environmental factors might also play a role.
66 citations
,
January 2000 in “Dermatology” This review discusses the nature, origin, and treatments of dandruff, with a focus on the role of *Malassezia* spp. and other triggering factors, but reports no new research findings.
December 2025 in “Biology Bulletin” In this study, researchers examined the skin of Baikal seals, identifying two main skin pathologies potentially linked to global warming and an unknown viral pathogen, suggesting immune inflammatory processes associated with environmental changes may be affecting these seals.
This review highlights that alopecia areata is influenced by genetic, autoimmune, and environmental factors, with emerging treatments like JAK-2 inhibitors showing promise for severe cases.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study explores a novel hypothesis for Male Pattern Baldness, suggesting that chronic tension in the scalp's Galea Aponeurotica creates a hypoxic environment affecting hair follicles, and proposes a Triad Therapeutic Protocol to address this underlying cause rather than just the symptoms.
18 citations
,
July 2022 in “Frontiers in Immunology” This review discusses the potential impact of volatile organic compound exposure on the onset and progression of autoimmune diseases and reports no new experimental findings.
5 citations
,
June 2002 in “Clinical and Experimental Dermatology” This presentation reviews the management of alopecia areata, emphasizing treatment challenges and options, but reports no new clinical results.
This study introduces diagnostic and therapeutic algorithms tailored for tailored management of alopecia areata based on patient-specific factors like age, disease severity, and quality of life.
4 citations
,
March 2025 in “Pediatric Dermatology” This review examines the clinical presentation of alopecia areata in children and compares it to adult-onset cases, noting that data on pediatric cases is scarce and often varies, with reported onset typically between ages 6 and 12.
7 citations
,
November 2018 in “British Journal of Dermatology” Alopecia areata is caused by immune system issues, and JAK inhibitors might help treat it.
March 2012 in “Journal of the American Academy of Dermatology” Treating ovarian-related inflammation may help hair regrowth in women with alopecia areata.
191 citations
,
May 2018 in “British journal of dermatology/British journal of dermatology, Supplement” This study reviewed recent theories on alopecia areata's pathogenesis, highlighting its autoimmune nature due to immune privilege disruption in hair follicles, and noted current treatments have limited efficacy with high relapse rates, underscoring the need for further research into its mechanisms for better therapies.
This chapter discusses the characteristics and impacts of acne vulgaris, acne rosacea, and acne inversa and reports no new clinical results.
This study summarizes common types of alopecia affecting many in China and suggests that factors like hormones, microorganisms, and immune dysregulation might contribute to hair loss, laying groundwork for better diagnosis and treatment approaches.
August 2021 in “Oxford University Press eBooks” This chapter discusses various skin functions and structures involved in protection, immune response, and homeostasis, but it reports no new research findings.
67 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This review discusses the causes, associated conditions, and treatment options for alopecia areata, such as corticosteroids and wigs, but reports no new clinical findings.
45 citations
,
April 2019 in “International Immunology” This review discusses the mechanisms behind alopecia areata and primary cicatricial alopecia and reports no new clinical results, aiming to guide the development of targeted treatments.
5 citations
,
March 2025 in “Pediatric Dermatology” This study found that alopecia areata is linked to genetic factors, specifically HLA haplotypes on chromosome 6, and involves immune privilege collapse at hair follicles which is mediated by the JAK-STAT pathway and pro-inflammatory cytokines like IFN-γ.
5 citations
,
August 2021 in “Zenodo (CERN European Organization for Nuclear Research)” This article reviews types, causes, and potential plant-based treatments for hair loss, but reports no new clinical findings.
2 citations
,
January 2017 in “Journal of Pigmentary Disorders” This article discusses vitiligo, reviewing its symptoms, possible causes, and classification, but reports no new clinical findings.
2 citations
,
April 2008 in “Experimental Dermatology” This article reviews the pathophysiology of hidradenitis suppurativa and suggests that a complex interplay of genetic, immunological, and biomechanical factors contributes to the condition, but presents no new clinical findings.
August 2026 in “Dermatology and Therapy” In this review, researchers outline the characteristics of scalp rosacea, an underrecognized inflammatory dermatosis, describing its multifactorial pathogenesis, diagnostic features, and management strategies, noting its clinical similarities with facial rosacea and the absence of standardized diagnostic criteria or therapeutic guidelines.
December 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that IL-1β may play a role in inflammatory signaling pathways in papulopustular rosacea, contributing to its pathogenesis.
July 2018 in “Elsevier eBooks” This article reviews the clinical presentation, diagnosis, and treatment options for discoid lupus erythematosus and reports no new clinical results.
January 2017 in “Springer eBooks” This article reviews the classification, pathogenesis, and treatment options for cutaneous lupus erythematosus and reports no new clinical findings.