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This review discusses environmental reprogramming and the plasticity of epithelial cells, emphasizing their potential for new cell therapy approaches; it reports no new experimental results.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

Results are not reported in this abstract, which outlines research investigating why diabetic mice experience suppressed hair follicle stem cell activation, potentially contributing to chronic diabetic wounds.

This study found that newborn mouse skin organoids can robustly grow hair in vivo, while adult organoids require specific interventions to restore their hair-forming ability.

This review provides a comprehensive synthesis of skin aging research, highlighting the interplay of genetic and environmental factors, cellular mechanisms, and advances in diagnostic and therapeutic strategies, while also addressing current debates and future directions in the anti-aging field.

This study observed that exosomes from adipose stem cells and dermal papilla cells altered the immune environment in hair follicles, promoting hair regrowth in mouse models and human follicle cultures.

New findings suggest targeting IL-23 could treat psoriasis, skin cells can adapt to new roles, direct conversion of skin cells to blood cells may aid cell therapy, removing certain tumor cells could boost cancer immunotherapy, and melanoma may have many tumorigenic cells, not just cancer stem cells.

This study found that the deletion of Med1 in dental epithelia causes a shift from dental to hair tissue development, suggesting the importance of Med1 in maintaining tissue-specific lineage.

This review discusses the various applications of chitosan-based materials in dermatology and highlights their potential as promising new materials but does not present new experimental results.

This study reviews evidence that in keloid development, transforming growth factor-β (TGF-β) drives fibroblast proliferation and fibrosis not only through the classical Smad-dependent pathway but also via equally important Smad-independent signaling cascades, suggesting these pathways as possible targets for more effective keloid therapies.

This study reports that corneal transient amplifying cells can be reprogrammed into epidermal cells capable of forming hair follicles in response to embryonic dermis signals.

This chapter reviews the presence and roles of stem cells in various body systems, focusing on their lifelong function in animals and humans, and reports no new experimental findings.

This article explores how extrafollicular environments and stem cell configurations influence hair and feather regeneration but provides no new experimental results.

In this review, the authors discuss how niche-specific immunometabolic regulation influences tissue repair across various organs by highlighting the complex, context-dependent interaction between immune metabolism and tissue-specific regenerative outcomes.

This study found that altering cell culture conditions to form three-dimensional papilla spheroids can restore the ability of human dermal papilla cells to induce hair growth in adult skin.

This review discusses recent advances in hair follicle biology, regeneration, and tissue engineering, highlighting emerging therapeutic opportunities, and reports no new experimental results.

This review discusses recent advancements in nanotechnology for treating hypertrophic scarring and atopic dermatitis, highlighting the potential of nanotherapeutic platforms in enhancing therapeutic effects by modulating the skin's microenvironment.

This review discusses environmental epigenomics and its potential impact on gene regulation and phenotypic outcomes, using the Avy mouse model to illustrate nutritional and environmental effects on the fetal epigenome without presenting new findings.

In this study, researchers observed that quiescent mouse embryonic fibroblasts showed reduced glycolysis but increased TCA cycle flux and mitochondrial respiration, with these changes linked to metabolic reprogramming involving yes-associated protein inhibition and malate cycle modulation, which supports extracellular matrix protein synthesis.

This study utilized a mouse model of traumatic brain injury to reveal that acute neurotrauma triggers widespread lipid metabolism reprogramming and storage lipid accumulation in microglial and monocyte populations, leading to lysosomal dysfunction, inhibited autophagy, and exacerbated inflammation through a pathological feedback loop.

This study observed that aging leads to significant structural and biological changes in the scalp's hair follicle environment in women, which may affect hair growth.

In this study, researchers developed a novel computational framework using deep reinforcement learning to identify strategies for cellular reprogramming in gene regulatory networks, showing its effectiveness in a model of immune response against infection.

This article discusses the coordinated roles of different epidermal stem cells and other cell types in the skin's wound healing process and reports no new experimental results.

In this study, researchers found that using bioinspired nanovesicles derived from inflammation memory-activated epidermal stem cells effectively promoted healing in diabetic wounds by reprogramming neutrophils to an anti-inflammatory phenotype in both laboratory and animal models.

This review discusses the hypothesis that polycystic ovary syndrome may originate in fetal life due to prenatal androgen exposure, but reports no new clinical results.

This review discusses recent advances in the role of dermal papilla cells and adipocyte lineage cells in hair regeneration, but it reports no new clinical results.

This review explores recent insights into how intrinsic gene oscillations and molecular interactions in hair follicle stem cells contribute to their regenerative potential, with potential implications for regenerative medicine, but reports no new clinical results.

This review examines the recent progress in using bioactive molecules for skin regenerative medicine and reports no new clinical results; the authors suggest this method could become a promising strategy for in situ skin regeneration.

In this study, researchers used a CRISPR-based method to correct mutations in the COL7A1 gene in stem cells from RDEB patients, restoring normal collagen expression in engineered skin grafts in mice.

This review highlights recent advancements in molecular understanding and treatment approaches for PCOS, including innovative drug delivery systems and AI-driven precision medicine, but provides no new clinical results.