November 2021 in “Dermatology Research and Practice” The study aims to understand the skin and hair characteristics of mothers and their babies, and how these may affect newborns' skin health and mothers' postpartum hair loss.
October 2020 in “Stem cells” The document concludes that DNA methylation and the mTOR pathway are important for stem cell function and could impact disease treatment.
January 2019 in “Obstetrics & Gynecology International Journal” Hormonal changes and conditions like polycystic ovarian syndrome are major causes of adult acne in women, with varying prevalence among different ethnicities.
365 citations,
November 2018 in “Journal of Allergy and Clinical Immunology” The document reviewed the role of the skin microbiome in atopic dermatitis (AD), highlighting that individuals with AD had a distinct microbial composition, notably increased Staphylococcus aureus colonization, which correlated with disease severity. It emphasized the importance of microbial diversity in maintaining skin health and suggested that targeting the microbiome could be a potential therapeutic strategy. Studies indicated that applying commensal organisms topically could reduce AD severity by decreasing S. aureus colonization. The findings underscored the need for further research into microbiome-based treatments and the impact of early-life microbial exposures on immune system development and disease susceptibility.
146 citations,
September 2013 in “Advances in nutrition” Bariatric surgery can cause serious mineral deficiencies, requiring better patient education and monitoring.
112 citations,
January 2004 in “The International journal of developmental biology” Feather patterns form through genetic and epigenetic controls, with cells self-organizing into periodic patterns.
103 citations,
December 2021 in “Journal of biological rhythms” Shift work disrupts the body's natural clock, leading to health problems.
96 citations,
September 2021 in “International Journal of Molecular Sciences” Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.
73 citations,
April 2019 in “Experimental Dermatology” The scalp's microorganisms significantly affect hair health and disease.
63 citations,
February 2017 in “ACS biomaterials science & engineering” Polydopamine is a safe, effective, and permanent hair dye that turns gray hair black in one hour.
58 citations,
November 2018 in “Cochrane library” Oral isotretinoin may slightly improve acne but increases the risk of side effects like dry lips and skin; more research is needed to understand its full risks and benefits.
54 citations,
January 2023 in “Signal Transduction and Targeted Therapy” New therapies are being developed that target integrin pathways to treat various diseases.
54 citations,
June 2020 in “Pharmaceutics” New nanocarriers improve drug delivery for disease treatment.
47 citations,
September 2022 in “European Heart Journal” Women may need different blood pressure guidelines than men for heart disease prevention.
44 citations,
September 2020 in “International Journal of Molecular Sciences” The document reviewed the molecular aspects of Polycystic Ovary Syndrome (PCOS) pathophysiology, focusing on genetics, hormones, and metabolism. It highlighted the complex interplay of genetic predispositions, hormonal imbalances, and metabolic dysfunctions contributing to PCOS. Key findings included the role of genes like CYP11a and CYP17, the impact of elevated anti-Müllerian hormone (AMH) levels, and the association of insulin resistance with PCOS. The review emphasized the need for novel therapies targeting the molecular causes of PCOS, as current treatments often failed to address issues like ovulation induction, insulin resistance, and androgenic symptoms. Promising substances for future treatments included inositols, GABA, kisspeptin, berberine, and naringenin. The document underscored the need for further research to optimize PCOS treatments.
39 citations,
April 1992 in “Development” Both cell and non-cell parts are important for rat whisker follicle regrowth.
32 citations,
January 2022 in “International Journal of Molecular Sciences” Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.
30 citations,
February 2022 in “Pharmaceutics” 3D bioprinting improves wound healing by precisely creating scaffolds with living cells and biomaterials, but faces challenges like resolution and speed.
20 citations,
April 2021 in “Journal of Womens Health” Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.
20 citations,
February 1994 in “In vitro cellular & developmental biology. Animal” Wool follicles can grow in a lab with the right nutrients and conditions.
19 citations,
August 2022 in “Forensic Science International Genetics” The study developed a model to predict age using DNA methylation markers from saliva and buccal cells, achieving a mean absolute error (MAE) of ±3.66 years. The model used seven CpG sites and was validated with 184 samples. Logistic regression achieved an 88.59% correct classification rate for tissue prediction. The study concluded that the combined model for both tissues is reliable for forensic applications, with a minimum of 10 ng of DNA required for accurate results. The final age predictor model is available online for forensic use.
19 citations,
January 2019 in “International Journal of Trichology” Indian dermatologists recommend treating common hair loss with a balanced diet, stress reduction, mild shampoos, and sometimes minoxidil and supplements.
18 citations,
June 2019 in “Clinical research in dermatology” Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.
15 citations,
February 2021 in “Frontiers in immunology” Leptin, a hormone from fat cells, affects immune responses and can influence skin diseases and hair growth.
14 citations,
May 2020 in “Archiv für Tierzucht” Researchers identified genes that may affect hair growth in Cashmere goats.
12 citations,
April 2020 in “Medical hypotheses” Men on 5-alpha-reductase inhibitors might have worse COVID-19 outcomes.
10 citations,
July 2022 in “Dermatology and Therapy” Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.
9 citations,
March 2022 in “Frontiers in Endocrinology” About 19.4% of Iranian women in the study have Polycystic Ovary Syndrome, with the most common type involving irregular periods and high male hormone levels, but their heart and metabolic health is similar to women without the condition.
9 citations,
January 2022 in “Biology” Male mice are more susceptible to autism-like changes from valproic acid than female mice.
9 citations,
August 2021 in “International journal of molecular sciences” PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.