research A Novel Animal Model of Desmoglein 1 (Dsg1) Deficiency Reveals an Essential Role for Dsg1 in Epidermal Barrier Formation
Dsg1 is essential for maintaining a healthy skin barrier in mice.
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research Elevated Expression of Osteopontin Splice Variants in Nonmelanoma Skin Cancer Compared to Normal Skin and Adult Keratinocytes
Nonmelanoma skin cancers have higher levels of certain osteopontin variants than normal skin.
research Neuropsychiatric Lupus: A Severe Manifestation of Systemic Lupus Erythematosus
Neuropsychiatric lupus is a severe form of lupus that needs strong treatment to improve life quality.
research Minoxidil
Minoxidil is effective for hair growth and safe for long-term use.
research A Patient with Diffuse Hair Loss
The patient's hair loss is most likely due to diffuse alopecia areata.
research Fluoroscopy-Induced Morphea
A man developed a painful skin condition after multiple heart procedures involving radiation.
research Generalized Granuloma Annulare: A Therapeutic Challenge. Our Experience in 12 Patients
Treating generalized granuloma annulare is difficult, with PUVA being the most effective option, but relapses are common.
research Segmental Cherry Angiomas Associated with Extragenital Lichen Sclerosus: A Report of Two Cases
Two patients had a rare combination of red skin spots and white scaly skin lesions not on the genitals.
research Ductal Breast Cancer in a Male Patient
An 86-year-old man with prostate cancer was diagnosed with a rare, low-grade breast cancer and underwent surgery but declined additional hormone therapy.
research Mouse Models with a Disrupted PTHrP Gene or a Disrupted PTH Gene (PTH−/− Mice)
PTHrP is important for bone formation and may be targeted for osteoporosis treatment and longevity therapies.
research Update on Medical Management of Benign Prostatic Hyperplasia
Castration is preferred for non-breeding male dogs with BPH, but other treatments are available with specific pros and cons.
research Court of Appeal Can Overrule Itself to Follow the EPO: UK Adopts EPO Stance on Second Medical Use Claims
The UK Court of Appeal ruled that new dosing regimens for drugs can be patented, aligning with the European Patent Office's approach.
research Australian Federal Court Rules on Trademark 'Deliberately Copied' from Overseas Market
Australian court ruled that Bickfords did not infringe on Monster Energy's trade mark because Monster was not sold or known in Australia at the time.
research Alopecia Areata In Infants: Is It Uncommon?
Alopecia areata in infants may be more common than previously thought.
research American Academy of Veterinary Dermatology and American College of Veterinary Dermatology Annual Meeting, Norfolk, Virginia, April 4-8, 2001
The meeting presented findings on effective treatments for various pet skin conditions and insights into the immune responses of dogs with atopic dermatitis.
research Drug Information Analysis Service: Effectiveness of Cromolyn Sodium in Treating Asthma in Children Under 2 Years Old
Cromolyn sodium's effectiveness for treating asthma in children under 2 is unclear, possibly more beneficial for older children, and further research is needed.
research Androgenetic Alopecia in a Patient with Klinefelter Syndrome: Case Report and Literature Review
Finasteride may effectively treat hair loss in Klinefelter Syndrome patients.
research Isolation and Structural Characterization of Degradation Products of Finasteride by Preparative HPLC, HRMS, and 2D NMR
Finasteride forms three new products under acidic stress.
research Post-Finasteride Syndrome: Outcomes of FDA Database
research Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice
Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
research The Rotterdam Study: Objectives And Design Update
The Rotterdam Study investigates diseases in older adults and has produced many research findings.
research The Hair Follicle as a Dynamic Mini-Organ
Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
research Growth of the Hair
Hair growth is cyclic and influenced mainly by local factors.
research Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis
VEGF helps hair grow and determines follicle size by increasing blood vessel growth.
research Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling
Fat-related cells are important for initiating hair growth.
research Rosacea: Etiology, Pathogenesis, And Subtype Classification
Rosacea is a skin condition with unclear causes, classified into four subtypes.
research Nerve-Derived Sonic Hedgehog Defines a Niche for Hair Follicle Stem Cells Capable of Becoming Epidermal Stem Cells
Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.
research The Rotterdam Study: 2018 Update on Objectives, Design, and Main Results
The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.
research Identification of the Cell Lineage at the Origin of Basal Cell Carcinoma
Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.
research Single-Cell Analysis Reveals Fibroblast Heterogeneity and Myeloid-Derived Adipocyte Progenitors in Murine Skin Wounds
The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.