2 citations
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December 2024 in “Journal of Photochemistry and Photobiology B Biology” This study suggests that pulsed wave photobiomodulation could be a promising treatment for androgenetic alopecia by enhancing dermal papilla cell function through specific light parameters, particularly frequency.
2 citations
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November 2023 in “Bioactive materials” The researchers reported that a newly developed ionic liquid-based microemulsion significantly improved the local delivery of copper peptides in mice, enhancing hair growth-related factor activation while offering a safer, non-invasive alternative to existing treatments for hair loss.
2 citations
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April 2022 in “Journal of Cosmetic Dermatology” This study found that de-saponinated Camellia seed cake extract promotes hair growth in vitro and in vivo by enhancing dermal papilla cell proliferation and modulating signaling pathways and growth factor expression.
2 citations
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August 2020 in “Journal of Nutritional Science and Vitaminology” In this study, yellow Chinese chive extract was observed to protect against acetaminophen-induced liver toxicity in mice by enhancing antioxidant pathways and reducing liver injury markers.
1 citations
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August 2024 in “Pharmaceuticals” This study found that goat placenta extract, when combined with PEGylated liposomes and microspicule gel, significantly promoted hair regrowth in patients experiencing hair loss due to chemotherapy by enhancing hair cell proliferation without causing skin irritation over a 12-week application period.
1 citations
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March 2023 in “Colloids and surfaces. B, Biointerfaces” This study reports that a collagen scaffold with p-Coumaric acid showed promising wound-healing effects in diabetic wound models by enhancing tissue regeneration and balancing collagen turnover.
1 citations
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September 2022 in “Evidence-based Complementary and Alternative Medicine” In this study, Gardenia florida fruit extract promoted hair growth in vitro and in vivo by enhancing hair growth-promoting gene expression and increasing hair follicle number, size, and depth in mice.
The researchers reported that PEG-FGF2 conjugates, particularly Compound 6, significantly enhanced stability, proliferation, migration, and wound healing activity compared to native FGF2, despite some reduction in bioactivity near crucial binding domains.
August 2026 in “International Journal of Molecular Sciences” This study found that Atractylodes macrocephala Koidz. extract promotes anagen entry and hair regrowth by enhancing dermal papilla cell activity and supporting hair cycle progression in a mouse model.
March 2026 in “Food Science and Biotechnology” In this study, oral administration of blue honeysuckle fruit extract was found to promote hair growth in mice by enhancing dermal papilla cell proliferation and activating β-catenin signaling, suggesting its potential use as a food or cosmetic product for hair regeneration.
November 2025 in “Medical alphabet” This study highlights that physiotherapeutic methods like low-intensity laser therapy, radiofrequency, and electrical stimulation show promising effectiveness in stimulating hair growth and treating telogen effluvium by enhancing cell activity, ATP synthesis, and transdermal drug delivery.
This review highlights that microtrauma, involving small intentional skin injuries, shows promise in stimulating hair growth in non-scarring alopecias by enhancing immune responses and increasing growth factor release, with methods like microneedling and PRP demonstrating efficacy.
March 2025 in “Molecules” This study found that Kyoh®, a flavonol-rich extract from rocket leaves, may promote hair growth by enhancing the expression of hair growth-related genes in laboratory conditions.
February 2025 in “Natural Product Communications” This study found that combining natural extracts significantly boosted the stem cell functions of dermal papilla cells by enhancing β-catenin stability, promoting hair growth potential in vitro.
November 2024 in “Aging Cell” In this study, researchers found that treating senescent human dermal papilla cells with dasatinib and quercetin improved their ability to regenerate hair follicles by depleting senescent cells and enhancing inductive potency, suggesting potential clinical applications for senolytic treatments in cell-based hair restoration therapies.
October 2023 in “Bioactive Materials” This study developed a novel liposome-based delivery system for Minoxidil and nitric oxide, which showed promising results in promoting hair regrowth in an androgenetic alopecia model by enhancing transdermal absorption, prolonging skin retention, and reducing inflammation.
This study showed that exosomes from hyaluronic acid-primed induced mesenchymal stem cells promote hair growth by enhancing proliferation and migration of hair follicle dermal papilla cells and modulating key growth factors and signaling pathways, potentially counteracting the effects of DHT-induced hair loss.
July 2022 in “http://isrctn.com/” Adding a cosmetic gel with caffeine, taurine, and growth factors to standard hair loss treatments could improve results.
January 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This study found that GDNF promotes hair formation and wound repair in mice by enhancing the function of bulge stem cells.
April 2016 in “Journal of Investigative Dermatology” This study found that a single high dose of oral vitamin D reduced UV-induced skin erythema and inflammation in humans by enhancing autophagy, suggesting new clinical avenues for skin repair.
January 2013 in “Zhongguo bingli shengli zazhi” In this rat study, Coriaria sinica Maxim extract significantly improved burn wound healing by enhancing epithelial growth and promoting hair regrowth, possibly through early-stage protein and mRNA expression changes.
January 2010 in “대한미용학회지” This study observed that Polygoni mulitiflori Radix water extracts accelerated hair regrowth in mice by enhancing enzyme activities and increasing IGF-1 gene expression related to hair growth.
October 2024 in “International Journal of Molecular Sciences” In this study, Rosa rugosa water extract improved hair length and thickness in a mouse model of DHT-induced alopecia by enhancing the expression of hair growth-promoting factors while inhibiting growth-suppressive proteins, suggesting its potential as a natural therapy for hair loss prevention.
92 citations
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September 2019 in “ACS nano” This study observed that a wearable electric stimulation device significantly promoted hair regeneration in rats and mice, outperforming conventional pharmacological treatments and enhancing growth factor secretion.
28 citations
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October 2011 in “International Journal of Molecular Medicine” In this study, adenosine was found to stimulate hair follicle growth in vitro by promoting growth factor expression, β-catenin activation, and downstream signaling pathways.
28 citations
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July 2021 in “Pharmaceutics” This study found that Morus alba root extract activates β-catenin in hair follicle dermal papilla cells, promoting the transition to the anagen phase and enhancing hair growth factor secretion.
115 citations
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August 2008 in “The Journal of Clinical Endocrinology & Metabolism” In this study, T3 and T4 were found to directly influence human hair follicles in vitro, enhancing keratinocyte proliferation, prolonging the hair growth phase, and affecting pigmentation.
88 citations
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July 2020 in “Frontiers in Cell and Developmental Biology” In this review, bioengineered materials incorporating growth factors and cytokines were reported to enhance wound healing by sustaining drug delivery, reducing dosage, and minimizing side effects compared to traditional treatments.
87 citations
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March 2005 in “Journal of Dermatological Science” This study found that the extract of Asiasari radix may promote hair growth in mice by enhancing protein synthesis, cell proliferation, and growth factor expression.
81 citations
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May 2019 in “Frontiers in Endocrinology” This study found that administering melatonin for 12 weeks to women with PCOS significantly reduced hirsutism, testosterone, and inflammation markers, while enhancing antioxidant levels compared to a placebo.