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The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Finasteride effectively treats baldness but may cause sexual side effects.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.

Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Botox increased hair count in men with baldness and might work by improving scalp blood flow.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

The document concludes that both internal stem cell factors and external influences like the environment and hormones affect hair loss and aging, with potential treatments focusing on these areas.

Cysteine-rich keratins evolved independently in mammals, reptiles, and birds for hard skin structures like hair, claws, and feathers.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

The evidence for using Low-Level Laser Therapy for hair loss is limited and more thorough research is needed.

APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.

Sarcoptes scabiei infection causes significant health and behavior changes in wombats.

Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.

A protein called PLC2 is important for the growth and development of plant roots influenced by auxin.

The CORT, FGF5, and CD36 genes are crucial for the cold weather adaptation of Yanbian cattle.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.