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Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.

The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Doxorubicin can block blood vessels from hair follicles, reducing skin tumor growth.

CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.

The FDA approved the first gene therapy for a blood disorder after overcoming early challenges and demonstrating patient benefits.

Enzymes called PADIs play a key role in hair growth and loss.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Different immune cells like platelets, mast cells, neutrophils, macrophages, T cells, B cells, and innate lymphoid cells all play roles in skin wound healing, but more research is needed due to inconsistent results and the complex nature of the immune response.

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.

Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.

Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.

Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.

Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.

Overexpression of HDGF in melanocytes does not cause cancer.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Different types of resting melanocyte stem cells have unique characteristics and vary in their potential to become other cells.

Different types of inactive melanocyte stem cells exist with unique characteristics and potential to develop into other cells.

Runx1 affects hair growth, cancer development, and autoimmune diseases in epithelial tissues.

Non-coding RNAs are crucial for skin development and health.

Using sharp tools and the right techniques in hair transplant surgery leads to less damage to hair follicles.

Apigenin may help promote hair growth and could treat hair loss.

Transplanted hair follicle stem cells improved brain function and reduced damage after a stroke in rats.

Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.

Take care of your hair as much as your face for a youthful look.

Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.

Laser ablation ICP-MS is effective for tracking trace elements in polar bear hair over time.

Good nutrition and essential trace elements like zinc, selenium, and iron are important for a strong immune system and reducing COVID-19 severity.