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The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Certain spices may help prevent and treat skin cancer, but more human trials are needed.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

Hormones and signaling pathways control sebaceous gland function and could help treat acne.

Hormone imbalance is linked to Hidradenitis Suppurativa, a skin condition, and treatments like anti-androgenic therapy and metformin can help. It's also suggested to check patients for insulin resistance and Polycystic Ovary Syndrome.

THSG from a Chinese plant helps with aging and related diseases.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Tadalafil and Finasteride may help treat aggressive melanoma.

Genes affecting wool fiber thickness in Angora rabbits were identified, which could help breed finer wool.

The most different genetic segment between Africans and East Asians is the EDA2R/AR region, with two main types influenced by population changes and natural selection, and linked to baldness.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Scientists found new genetic areas that affect how rice root hairs grow and develop.

Long COVID causes a wide range of long-lasting symptoms that change over time and are hard to diagnose and treat.

Metal organic frameworks-based scaffolds show promise for tissue repair due to their unique properties.

Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.

MOF controls key genes for skin development by regulating mitochondrial and ciliary functions.

The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

The β-sitosterol hair gel is effective and promising for treating hair loss.

Hair follicles could be used to noninvasively monitor our body's internal clock and help identify risks for related diseases.

Vesicular carriers like liposomes may improve cosmetic skin treatment delivery and effectiveness but need more human research.

AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.

New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.

The VEGF +405G allele may increase the risk of PCOS in South Indian women.

Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.

The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.

The CAP1 gene helps control ammonium levels and is necessary for the proper growth of root hairs in Arabidopsis.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.