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This review highlights recent advancements in molecular understanding and treatment approaches for PCOS, including innovative drug delivery systems and AI-driven precision medicine, but provides no new clinical results.

This review highlights emerging evidence that biophysical and metabolic cues, such as oxygen levels and tissue mechanics, significantly influence skin stem cell behavior, which is crucial for developing advanced wound healing therapies beyond traditional infection and inflammation control.

This study found that prolonged intermittent fasting in diet-induced obese mice led to increased levels of inositol monophosphates in white adipose tissue, improved insulin sensitivity, and reduced body weight and fat mass, suggesting a novel metabolic adaptation mechanism.

In laboratory research, investigators found that apoptotic vesicles from interleukin-10-treated fibroblasts promote wound healing and reduce fibrotic scarring by enhancing mitochondrial function, modulating collagen composition, and inhibiting the Hedgehog signalling pathway, offering potential for regenerative medicine applications.

This study highlights a close link between metabolic syndrome, characterized by conditions like obesity and hypertension, and various inflammatory skin diseases, suggesting that mitochondrial dysfunction plays a key role in their pathogenesis and could be a target for new therapies.

This article discusses the treatment options for women with polycystic ovarian syndrome and notes the need for further research to improve patient management.

This study found that in PCOS patients, variations in the lipin 1 gene, particularly the intron 1 SNP, may protect against insulin resistance and glucose intolerance, highlighting a potential genetic factor in the disorder's cardiometabolic complications.

This study identified a group of dermal fibroblasts near hair follicle stem cells in mice that facilitate hair regeneration by creating a biomechanically compliant extracellular matrix, enhancing stem cell activation and promoting a positive feedback loop for tissue regeneration.

This study showed that regulation of adipose androgen generation via AKR1C3 may contribute to a cycle of hyperinsulinaemia and lipid accumulation in women with PCOS.

This article reviews the clinical features, diagnostic criteria, and possible genetic and environmental influences of polycystic ovary syndrome but provides no new research findings.

This review discusses the role of androgens in the progression of cardiovascular disease and explores novel therapeutic targets without reporting new clinical results.

This review discusses the role of DHEA in intracrinology, highlighting its impact on breast and prostate cancer treatment and potential as a menopause therapy, but reports no new research findings.

This review highlights that medical complications, notably in anorexia nervosa, are common and often serious in patients with eating disorders, affecting multiple organ systems.

This review discusses guidelines for androgen use in women and concludes that more research is needed before recommending testosterone due to insufficient evidence on safety and efficacy.

This study found that PCOS patients had higher amounts of central abdominal fat compared to weight-matched controls, which was associated with increased insulin resistance.

This review discusses the multifaceted actions of metformin in polycystic ovary syndrome and reports no new clinical results; the authors emphasize metformin's potential benefits in both cardiometabolic and reproductive aspects of PCOS.

This study found that combining liraglutide with metformin led to greater weight loss and waist circumference reduction than either treatment alone in obese women with PCOS resistant to metformin monotherapy.

This article reviews the care of transgender patients, encompassing diagnosis, treatment options, and challenges in health care access, but does not present new research findings; the authors emphasize the critical role of providers in addressing transgender health needs.

This review discusses how changes in hair and skin may indicate underlying vitamin deficiencies and emphasizes the need to identify populations at risk for these deficiencies; it reports no new results.

This article discusses the association between hypertension and polycystic ovary syndrome, highlighting the need for managing related risk factors, but reports no new clinical results.

The study found that severe insulin resistance and premature diabetes are common in patients with PCNT genetic defects, primarily affecting those over four years old, while not impacting early insulin signaling in adipocytes.

This review discusses treatment options for female pattern hair loss, emphasizing the importance of early intervention and the benefits of combined therapies, but reports no new clinical results.

This review discusses the International Evidence-Based PCOS Guidelines, which aim to improve diagnosis and management of PCOS and its associated comorbidities, noting the importance of early intervention and healthy lifestyle changes; it reports no new results.

This review discusses normal menstrual variations and common menstrual disorders in adolescent girls, focusing on symptoms, evaluation, and management, but does not present new clinical results.

This review discusses the impact, pathophysiology, and health risks of obesity and the metabolic syndrome in polycystic ovarian syndrome, emphasizing the potential life-saving benefits of recognition and treatment, but it reports no new results.

This review discusses androgen manipulation strategies for conditions like benign prostatic hyperplasia and prostatic carcinoma but reports no new clinical results.

This study found that maternal sub-maintenance nutrition reduced the density and branching ratio of secondary wool follicles in Merino sheep fetuses and identified genes potentially involved in these processes.

This review discusses the evaluation of hyperandrogenemia in women and hypogonadism in men across different life stages and presents biomarkers used for diagnosing male hypogonadism, reporting no new clinical results.

This review discusses the links between sex hormones, metabolic syndrome, and skin conditions, and reports no new clinical results; the authors recommend monitoring patients with specific skin conditions for metabolic complications.

This study observed that patients using Erol(®) Energy shampoo and tonic reported improved symptoms of scalp irritation and rated product tolerance as good to excellent.