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The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

Lowering testosterone speeds up wound healing in male mice.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

One minoxidil-sensitive potassium channel exists in human hair follicles.

Female Pattern Hair Loss affects women's self-esteem and needs more research for better treatment.

Diazoxide, minoxidil sulphate, and cromakalim relax rat blood vessels by opening K+ channels, with some differences in their actions.

NF-κB is crucial for zebrafish heart repair, affecting heart cell growth and repair processes.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.

New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.