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Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

SkQ1 antioxidant improved health and lifespan in mice.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

Melanocyte stem cells are crucial for skin pigmentation and have potential in disease modeling and regenerative medicine.

Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.

A specific signal from hair cells controls the tightening of the surrounding muscle, which is necessary for hair shedding.

A new hair restoration technology was found to effectively increase hair thickness, density, and growth, while reducing hair loss and improving scalp health, with no side effects.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

The gene Endothelin 3 makes mice's fur darker by increasing pigment cells and pigment levels.

EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.

Stem cells can help other stem cells by producing supportive factors.

A woman with alopecia totalis regrew dark hair in bands after using a corticosteroid ointment.

PCE-DP brightens skin and promotes hair growth by enhancing cell growth and reducing melanin uptake.

Cultured skin cells can trigger hair growth and the amount of certain proteins they produce affects their ability to regenerate hair follicles.

Cultured dermal papilla cells can regenerate hair follicles and sustain hair growth.

Using existing drugs for new purposes could be a cost-effective way to treat chest pain and non-clogged heart arteries, with some drugs for lung blood pressure showing promise but needing more testing.

Skin lesions in Carney Complex are caused by a gene change in some skin cells that leads to increased pigmentation and may lead to tumors.

The study found that higher levels of ET-1 and SCF in early-stage dermal papilla cells improve their ability to regenerate hair follicles.

Dermal factors are crucial in regulating melanin production in skin.

Genetic analysis of rabbits identified key genes for traits like coat color, body size, and fertility.

Cultured dermal papilla cells can regenerate hair follicles and sustain hair growth.

White hirsute women with PCOS have higher insulin resistance, but similar nitric oxide and fibrinogen levels compared to those with idiopathic hirsutism.

Ustekinumab significantly improved sexual function and quality of life for people with moderate to severe psoriasis.

Methotrexate treatment for rheumatoid arthritis has a serious infection rate of about two per 100 patient-years.

Lower nitric oxide and higher fibrinogen found in hirsute women; impaired sexual function in 22.6% of hair loss patients, linked to psoriasis severity.

Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.

Cat color patterns are determined early in development by gene expression and epidermal changes, with the Dickkopf 4 gene playing a crucial role.

Vitamin D boosts a specific gene activity in kidney cells that could improve heart and kidney function.

Hair color is determined by different melanins and changes with age.

Gene regulation could revolutionize hair color by altering pigmentation from within.