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Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.

Removing the ROBO4 gene in mice reduces skin inflammation and hair loss by affecting certain inflammation pathways and gene expression.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Finasteride side effects in young men may be linked to specific gene variations.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Blocking adenosine A2B receptor may prevent or treat hearing loss.

The research identified key molecules that help hair matrix and dermal papilla cells communicate and influence hair growth in cashmere goats.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Applying InlB321/15 to wounds sped up healing in mice.

Stress can stop hair growth in mice, and treatments can reverse this effect.

TLR4 is important in aging-related diseases and could be a new treatment target.

Pig skin cells can turn into mesodermal cells but lose their ability to become neural cells.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

Lowering testosterone speeds up wound healing in male mice.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.

NMN could potentially treat hair loss by reducing oxidative stress and improving cell health.

The document concluded that FDA-approved treatments like minoxidil and finasteride are effective for hair loss, while the effectiveness of natural remedies and other non-approved treatments is not well-supported by evidence.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Plant-based products can improve hair and skin health without harmful side effects.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.