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Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.

PDGF-BB helps young melanocytes grow but stops mature ones from growing, and it makes melanocytes more specialized.

Ferrous Ferric Chloride may improve skin cell function and increase hair growth in mice.

Segmental Vitiligo is a stable, early-onset form of vitiligo that responds well to early treatment and is ideal for repigmentation studies.

The document explains the genetic causes and characteristics of inherited hair disorders.

Skin problems like psoriasis and systemic sclerosis can increase the risk of heart disease, so doctors should watch for heart risks in patients with these conditions.

New therapies show promise for wound healing, but more research is needed for safe, affordable options.

Patients with pernio have lower vitamin B12 and ferritin levels than healthy people.

Women with PCOS often have insulin resistance, abnormal lipid levels, and a higher risk of diabetes and heart disease; lifestyle changes and medication like metformin can help manage these risks.

Wound healing is complex and requires more research to enhance treatment methods.

Hyperpigmentation is common in pregnancy and may not fully fade after birth; melasma, also frequent, can persist but has limited treatment options during pregnancy.

The document concludes that managing skin conditions during pregnancy is important and requires specialized care.

Wnt3a activates certain genes in hair follicle cells, including a newly discovered one, EP2, which may affect hair growth.

Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.

The review highlights the importance of stem cells in hair health and suggests new treatment strategies for hair loss conditions.

Diuretics help the body get rid of excess salt and water by acting on the kidneys in different ways.

Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

Keratinocytes control how melanocytes work.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

A new skin-whitening agent using a peptide from wheat is safe and effective at reducing skin pigmentation.

Safflower has been used in traditional medicine for centuries and shows promise in treating heart, brain, and inflammatory conditions, but more research is needed to ensure its safety.

ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.

Hormones cause hair loss by affecting cell growth and weakening cell attraction.

Cannabinoids may help treat various skin conditions.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

Stem cells can help other stem cells by producing supportive factors.

Fibroblasts are important in healing diabetic wounds, but high sugar levels can harm their function and slow down the healing process.