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Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.

Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.

Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.

Hair follicle regeneration possible, more research needed.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.

Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.

Proteins from stem cells improved hair growth in patients with hair loss.

SCF and ET-1 together significantly increase skin pigmentation and melanin production.

New drugs for heart disease may be developed from molecules secreted by stem cells.

Human hair follicle cells can be successfully transformed into different types of cells, but not more efficiently than other adult cells.

Ozone therapy might improve cancer treatment and reduce its side effects.

Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.

A mix of 5-aminolevulinic acid and iron ion can speed up hair growth.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.

Burn scars heal abnormally and more research is needed to find better treatments.