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Growth factor treatments are increasingly used in medicine but require more research to fully understand their mechanisms.

Nitric oxide is important for skin functions and both helps protect against and contributes to skin inflammation and sensitization.

Using microneedling with PRP improves skin and hair conditions more than microneedling alone.

Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.

The document concluded that FDA-approved treatments like minoxidil and finasteride are effective for hair loss, while the effectiveness of natural remedies and other non-approved treatments is not well-supported by evidence.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Targeted cancer therapies often cause serious skin problems that need careful management.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Platelet-rich plasma may help with hair growth and skin quality but more research is needed to confirm its effectiveness.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.

Squarticles effectively deliver hair growth drugs to follicles and dermal papilla cells.

Apoptosis is crucial for healthy skin and treating skin diseases.

Finasteride may help treat chronic CSC, improving vision.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Finasteride and minoxidil work best together for hair loss.

Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.

Macrophages are essential for successful skin growth in reconstructive surgery.

Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.

Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.

Safflower (Carthamus tinctorius) extract helps hair grow and could be used in hair products.

A study found that minoxidil can damage the hearts of dogs and pigs, cautioning its use in humans.

Fetal wounds heal without scarring because of different biological factors, which could help improve adult wound healing.

Tannic acid helps wounds heal faster in rats by activating certain cell signals and reducing inflammation.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.