research Locally Delivered Umbilical Cord Mesenchymal Stromal Cells Reduce Chronic Inflammation in Long-Term Nonhealing Wounds: A Randomized Study
Umbilical cord cells safely improve healing in long-term nonhealing wounds better than a placebo.
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research Novel ALK5 Inhibitor TP0427736 Reduces TGF-β Induced Growth Inhibition in Human Outer Root Sheath Cells and Elongates Anagen Phase in Mouse Hair Follicles
TP0427736 may help treat hair loss by blocking a specific protein and promoting hair growth.
research Mesenchymal Stem Cells From Mouse Hair Follicles Reduce Hypertrophic Scarring in a Murine Wound Healing Model
Mouse stem cells from hair follicles can improve wound healing and reduce scarring.
research Early-Stage Bilayer Tissue-Engineered Skin Substitute Formed by Adult Skin Progenitor Cells Produces an Improved Skin Structure In Vivo
Adult skin cell-based early-stage skin substitutes improve wound healing and hair growth in mice.
research Small Intestinal Organoid-Derived SP Cells Contribute to Repair of Irradiation-Induced Skin Injury
Intestinal stem cells can help repair skin damage from radiation.
research Effects of 1α,25-Dihydroxy-Vitamin D3 and Calcipotriol on Organotypic Cultures of Outer Root Sheath Cells: A Potential Model to Evaluate Antipsoriatic Drugs
Vitamin D compounds may help treat psoriasis by promoting skin cell differentiation.
research Stem Cell Therapies in Basic Science and Translational Medicine: Current Status and Treatment Monitoring Strategies
Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.
research Equine Hoof Stem Progenitor Cells (HPC) CD29+/Nestin+/K15+ – A Novel Dermal/Epidermal Stem Cell Population With a Potential Critical Role for Laminitis Treatment
Newly found stem cells in horse hooves show promise for treating a hoof disease called laminitis.
research Stem Cells in Tissue Engineering
Different stem cells have benefits and challenges for tissue repair, and more research is needed to find the best types for each use.
research Adipose-Derived Stem/Stromal Cells in Regenerative Medicine
Fat tissue stem cells show promise for repairing different body tissues and are being tested in clinical trials.
research Metformin Promotes Mechanical Stretch-Induced Skin Regeneration by Improving the Proliferative Activity of Skin-Derived Stem Cells
Metformin helps improve skin regeneration by increasing the growth of skin stem cells.
research Characterization of CD4+ Stem Cells of the Skin and Their Role in Skin Homeostasis and Tumorigenesis
CD4+ skin cells may be precursors to basal cell carcinoma.
research Recombinant Human Growth Hormone Promotes Burn Wound Repair by Regulating Vascular Endothelial Growth Factor and Microvessel Density
Recombinant human growth hormone helps burn wounds heal faster by increasing blood vessel growth.
research Keratinocytes and Adipose-Derived Mesenchymal Stem Cells: The Heir and the Spare to Regenerative Cellular Therapies for Difficult-to-Heal Skin Wounds
Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.
research Multi-View Light Sheet Fluorescence Microscopy for Imaging Cellular Self-Assembly in Spheroids of Human Hair Follicle Dermal Papilla Cells and Keratinocytes
The technique effectively shows how human skin and hair cells form into ball-like structures.
research Single-Cell Sequencing Reveals the Intermediate Cell State and Function of Dermal Papilla Cells in the Hair Follicle Cycle of Cashmere Goats
Researchers found four key stages of cell development that are important for hair growth and shedding in cashmere goats.
research cAMP Response Element-Binding Protein 1 (CREB) Is a β-Catenin-Regulated Transcription Factor in Squamous Cell Carcinoma (SCC) Cells
CREB, a protein that can promote cancer traits, is controlled by β-catenin in skin cancer cells.
research Stem Cells in the Body
Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.
research Stem Cells in the Skin
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
research Adipose-Derived Stem Cells and Their Secretory Factors for Skin Aging and Hair Loss
Fat-derived stem cells may help treat skin aging and hair loss.
research Adipose-Derived Stem Cells and Their Secretory Factors for Skin Aging and Hair Loss
Fat-derived stem cells and their secretions show promise for treating skin aging and hair loss.
research Transforming Growth Factor-Beta in Stem Cells and Tissue Homeostasis
TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
research Hair Follicle Stem Cells: Walking the Maze
Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
research Regulatory T Cells in Skin: Role of Foxp3+ CD4+ Tregs in Skin Homeostasis and Immune Tolerance
Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.
research Circadian Clocks: From Stem Cells to Tissue Homeostasis and Regeneration
Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.
research Review of Hair Follicle Dermal Papilla Cells as In Vitro Screening Model for Hair Growth
Dermal Papilla cells are a promising tool for evaluating hair growth treatments.
research Exosomal MicroRNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation
Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.
research Proinflammatory Cytokines Regulate Epidermal Stem Cells in Wound Epithelialization
Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.
research Effect of 5α-Dihydrotestosterone and Testosterone on Apoptosis in Human Dermal Papilla Cells
High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.
research Differential Expression Between Human Dermal Papilla Cells from Balding and Non-Balding Scalps Reveals New Candidate Genes for Androgenetic Alopecia
New genes found linked to balding, may help develop future treatments.