59 citations,
February 2012 in “Journal of Dermatological Science” Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.
TLR3 signaling enhances the immunosuppressive properties of human periodontal ligament stem cells.
April 2017 in “Journal of Investigative Dermatology” Fisetin may help treat psoriasis and reduce skin inflammation.
48 citations,
February 2013 in “Molecular and Cellular Endocrinology” The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.
20 citations,
January 2014 in “Journal of Cosmetics, Dermatological Sciences and Applications” Using adipose derived stem cells and growth factors in hair transplants may improve healing and hair growth.
1 citations,
January 2010 in “Springer eBooks” M-CSF-stimulated myeloid cells can turn into skin cells and help heal wounds and regrow hair.
Myeloid cells can turn into skin and hair cells to help heal wounds.
238 citations,
March 2013 in “Development” Fat cells help recruit healing cells and build skin structure during wound healing.
89 citations,
January 2009 in “Advances in Clinical Chemistry” Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.
46 citations,
December 2018 in “Genes & Development” Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.
26 citations,
December 2016 in “Pharmacology & Therapeutics” New drugs for heart disease may be developed from molecules secreted by stem cells.
25 citations,
April 2021 in “The EMBO Journal” Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.
25 citations,
November 2020 in “Experimental eye research/Experimental Eye Research” Different types of cells in the eye express specific keratins at various stages of development.
16 citations,
January 2018 in “International Journal of Trichology” Minoxidil may help treat hair loss by reducing inflammation-related gene activity in skin cells.
15 citations,
January 2015 in “Stem cells international” Human hair follicle stem cells can be turned into red blood cells.
14 citations,
November 2019 in “Mediators of inflammation” IL-6 from stem cells helps repair skin and grow hair.
8 citations,
February 2017 in “International journal of molecular sciences” Mollusc egg extract helps skin and hair cells grow and heal.
5 citations,
February 2017 in “Biomolecules & Therapeutics” 4-O-Methylhonokiol helps protect skin cells from growth-stopping effects of a protein by regulating growth-related pathways.
5 citations,
August 2013 in “InTech eBooks” KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.
3 citations,
July 2022 in “Stem Cell Research & Therapy” Turning off a specific gene in stem cells speeds up skin healing by helping cells move better.
2 citations,
December 2003 in “Medical electron microscopy” The skin and mucous membranes can regenerate over the basement membrane after damage, using nearby surviving cells.
1 citations,
January 2018 in “Elsevier eBooks” The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.
March 2020 in “Central European Journal of Biology” The study found that stem cells and neutrophils are important for regenerating hair follicle structures in mice.
480 citations,
August 2014 in “Nature Biotechnology” Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.
301 citations,
February 2019 in “Nature Communications” The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.
286 citations,
June 2012 in “Nature Immunology” Hair follicles help attract immune cells to the skin during stress.
271 citations,
May 2019 in “Cells” The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.
211 citations,
November 2018 in “Nature Cell Biology” Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.
137 citations,
April 2015 in “Nature Reviews Molecular Cell Biology” Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.