5 citations
,
October 2021 in “PubMed” This study found that exosomes derived from human adipose stem cells significantly enhanced the proliferation and migration of dermal papilla cells compared to those from platelet-rich plasma, suggesting potential benefits for hair loss treatment.
4 citations
,
August 2024 in “Dermatological Reviews” This review explores the basic science and therapeutic potential of stem cells, platelet-rich plasma, and exosomes in regenerative medicine, highlighting their promising roles in skin regeneration and repair but noting a need for further research.
3 citations
,
January 2023 in “Regenerative Medicine” This review discusses the potential role of exosomes in aesthetic medicine for skin rejuvenation and hair restoration, but reports no new clinical findings and emphasizes the need for further studies with regulatory oversight.
3 citations
,
May 2022 in “Dermatologic surgery” This review examines the use of exosomes in skin rejuvenation and hair regeneration but reports no new clinical results, noting challenges in purification and practical use for clinical applications.
3 citations
,
June 2020 in “Pharmacognosy Journal” In this study, researchers developed ethosomes containing Phyllanthus emblica extract and found them to have beneficial properties, including high entrapment efficiency and antioxidant activity, suggesting potential as an alternative product for preventing hair loss.
3 citations
,
January 2004 in “Zhōnghuá yàoxué zázhì” In this study, ethosomes were found to significantly enhance the transdermal penetration and skin accumulation of finasteride compared to liposomes and other control solutions.
2 citations
,
February 2025 in “Advances in Cosmetic Surgery” Exosome therapies could help with skin and hair issues, but more testing is needed.
2 citations
,
December 2024 in “Neural Regeneration Research” This research review highlights the potential of exosome therapy to transform stroke treatment, reporting that in animal models, exosomes can reduce neuroinflammation, oxidative stress, and cell death, while promoting brain repair and regeneration. However, more evidence is needed before clinical applications in humans are established.
2 citations
,
January 2022 in “Oxidative Medicine and Cellular Longevity” This study suggests that exosomes from dermal papilla cells can regulate hair follicle stem cell proliferation via the Wnt3a/β-catenin signaling pathway, potentially informing treatment for human hair problems.
2 citations
,
January 2022 in “Stem cell biology and regenerative medicine” This review discusses the potential of extracellular vesicles from various sources as promising candidates for hair growth stimulation but notes that clinical trials are needed to confirm their effectiveness and safety.
2 citations
,
January 2021 1 citations
,
December 2025 in “Stem Cell Research & Therapy” This study found that hucMSC-EXOs delivered via intratympanic injection effectively target vestibular sensory tissues, significantly reducing gentamicin-induced balance issues and high-frequency hearing loss, with some measured outcomes surpassing those achieved with dexamethasone.
1 citations
,
December 2025 in “Journal of Pharmacology and Experimental Therapeutics” Exosomes show promise in improving skin health and appearance.
1 citations
,
April 2025 in “JOJ Dermatology & Cosmetics” In this study, researchers evaluated the efficacy of a collagen booster used alongside CO2 fractional laser treatment for skin aging, finding that the combination treatment affected the vascularization and healing process of the skin on a healthy adult's forearm.
1 citations
,
March 2025 in “Journal of Cosmetic Dermatology” This case report describes promising results in treating poliosis circumscripta with exosomes and fractional picosecond laser, showing significant hair regrowth and repigmentation, though spontaneous repigmentation cannot be ruled out.
1 citations
,
January 2025 in “Regenerative Biomaterials” In this study, researchers found that exosomes derived from Pinctada martensii mucus can effectively inhibit melanin production in melanoma cells and zebrafish without adverse effects, potentially offering a promising therapeutic strategy for treating pigmentary disorders by modulating the NF-κB signaling pathway.
1 citations
,
July 2024 in “Journal of Associated Medical Sciences” This review highlights the mechanisms and therapeutic potential of mesenchymal stem cell-derived exosomes in regenerative medicine and discusses recent advances in their use for treating various ailments, without presenting new clinical findings.
1 citations
,
January 2022 in “Biocell” This article discusses the potential of mesenchymal stem cell-derived exosomes (MSCs-exosomes) in regenerative medicine, highlighting their beneficial effects like anti-inflammatory and tissue regeneration properties, and noting challenges such as exosome isolation and safety evaluation that need addressing.
1 citations
,
January 2022 in “Oxidative Medicine and Cellular Longevity” This study found that hair follicle-derived mesenchymal stem cells can alleviate pyroptosis and improve ulcerative colitis symptoms in mice, suggesting potential new treatments for the condition.
1 citations
,
May 2020 in “Research Square (Research Square)” This study found that human bone marrow mesenchymal stem cell-derived exosomes promote cutaneous wound healing in rats by inhibiting the TGF-β/Smad signaling pathway.
1 citations
,
January 2020 in “Skinmed” This review discusses the potential of exosome therapy for treating androgenetic alopecia but reports no new clinical results, highlighting the need for trials to confirm its efficacy and safety.
1 citations
,
October 2018 in “InTech eBooks” This chapter reviews ethosomes for targeted drug delivery to the scalp in androgenetic alopecia and reports no clinical results; the authors emphasize reducing systemic side effects.
1 citations
,
January 2007 in “Zhōnghuá yàoxué zázhì” In this study, ethosomes were more effective than liposomes for delivering finasteride through human skin, showing higher transdermal flux and accumulation, especially in deeper skin layers.
August 2026 in “Mendeley Data” This review article systematically summarizes current knowledge on using hair follicle neural crest stem cells and their exosomes for repairing peripheral nerve injuries, focusing on the molecular mechanisms and potential applications. The dataset includes comparison tables and diagrams to visually present findings from existing research.
August 2026 in “Mendeley Data” This review systematically assembles recent insights into the use of hair follicle neural crest stem cells and their exosomes for peripheral nerve injury repair, highlighting molecular mechanisms and possible translational applications, with comprehensive tables and diagrams summarizing existing literature.
August 2026 in “DOAJ (DOAJ: Directory of Open Access Journals)” This review summarizes the potential of exosome-based therapies as a promising treatment for androgenetic alopecia, emphasizing their role in modulating key signaling pathways, but highlights the need for further evidence to confirm their efficacy and safety.
July 2026 in “International Science Journal” This review discusses current findings in regenerative dermatology, noting promising results for therapies using exosomes and polynucleotides in skin rejuvenation and healing, while highlighting the need for more standardized protocols and long-term studies to confirm their effectiveness and safety.
July 2026 in “Open Access CRIS of the University of Bern” This study reviewed 80 preclinical and clinical studies and found that exosome-mediated treatments show promise for hair regeneration in alopecia by boosting hair density and thickness with generally mild side effects, but call for further research and standardization before widespread clinical use.
July 2026 in “Periodontology 2000” This study reviewed exosome-mediated interventions for alopecia, finding that they enhance hair regeneration by stimulating key pathways and improving hair properties, with clinical studies showing increased hair density and patient satisfaction, though further trials are needed for widespread clinical use.
July 2026 in “Dermatological Reviews” This narrative review highlights the potential of exosomes as a promising platform for precision diagnostics, regenerative medicine, and targeted therapeutics in dermatology, while noting challenges such as standardization, manufacturing, and regulatory approval that must be resolved before widespread clinical use.