20 citations,
March 1990 in “JAMA” Topical eye β-blockers may cause hair loss.
6 citations,
July 2016 in “Gynecological Endocrinology” PSA levels are higher in women with PCOS, but FAI is a more accurate marker for diagnosis.
3 citations,
May 2014 in “InTech eBooks” Copper deficiency may cause hair loss, and treating it could involve nutrition and hormones.
45 citations,
January 2012 in “Experimental Dermatology” Human hair follicles switch between active and resting phases unpredictably.
38 citations,
January 1997 in “Gynecological Endocrinology” Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.
20 citations,
October 2017 in “Clinical Endocrinology” The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.
20 citations,
August 1987 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Aldactone was more effective in reducing hair growth in women with hirsutism than Diane, despite having less impact on hormone levels.
18 citations,
November 2016 in “Neuromuscular Disorders” Patients with myotonic dystrophy often have skin problems that suggest early aging and vitamin D issues, and the severity of these problems is linked to their genetic condition and vitamin D levels.
16 citations,
February 2018 in “European Journal of Endocrinology” Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.
11 citations,
July 2015 in “Gene” DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.
1 citations,
October 2023 in “Egyptian Journal of Immunology” PCOS is linked to low-grade chronic inflammation.
The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.
Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.
1540 citations,
October 2008 in “Fertility and Sterility” The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.
243 citations,
October 2003 in “Developmental biology” Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.
233 citations,
November 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.
218 citations,
December 2011 in “Advances in Urology” The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.
157 citations,
May 2021 in “Endocrine Reviews” Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.
130 citations,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).
117 citations,
May 2017 in “Human Reproduction Update” The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.
63 citations,
November 1999 in “British journal of dermatology/British journal of dermatology, Supplement” Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.
54 citations,
August 2017 in “Gynecological Endocrinology” Lifestyle changes and weight loss are key for treating PCOS-related metabolic issues and infertility, with various medications available for specific symptoms.
30 citations,
January 2015 in “BioMed Research International” Continuous light exposure in rats leads to PCOS-like symptoms and suggests sleep habits might affect the disorder's development.
28 citations,
August 2003 in “Steroids” Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.
27 citations,
April 2017 in “European journal of endocrinology” The research found that MRI and certain hormone levels can help tell apart ovarian tumors from hyperthecosis in postmenopausal women, but tissue analysis is still needed for a definite diagnosis.
26 citations,
February 2009 in “Drug Development Research” 17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.
25 citations,
June 2018 in “Journal of The American Academy of Dermatology” Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.
25 citations,
June 2012 in “Endocrine” PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.
22 citations,
March 2000 in “Clinics in Dermatology” Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.
22 citations,
April 1998 in “Dermatologic Clinics” Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.