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The guidelines help doctors diagnose and treat hormone-related disorders in women.

Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.

17β-estradiol can reduce inflammation in the skin.

Polycystic Ovary Syndrome (PCOS) is not very common among Iranian women, but it's important to prevent it because of the risk of heart disease and infertility.

Both metformin and pioglitazone improve PCOS symptoms, but pioglitazone is a good alternative for those who can't take metformin.

Different types of RNAs are found in varying amounts in patients with Polycystic Ovary Syndrome, suggesting they could be important in the disease's development and potentially used as disease markers.

Skin cancer often starts from Lgr5+ progenitor cells.

Researchers found four natural compounds that can change DHT levels in prostate cancer cells.

Plant sterols have health benefits like lowering cholesterol, but more research is needed to understand their effects and improve their extraction and sustainability.

Genes and epigenetic changes are important in the development of Polycystic Ovary Syndrome.

YAP and TAZ are crucial for skin cell growth and repair.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Oral contraceptives and antiandrogens are effective for treating hirsutism, with antiandrogens being the most effective.

Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

The conclusion is that women under 35 should start fertility checks after 12 months of trying to conceive, women over 35 after 6 months, and women over 40 should start immediately. The checks should include ovulation status, reproductive tract structure, and male partner's semen evaluation.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

LPA3 signaling in the uterus is crucial for placental formation and fetal development.

Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.

High Nesfatin-1 and low Vitamin D may increase blood pressure and heart rate in women with PCOS.

Insulin resistance is a complex condition that can lead to many diseases and has few treatment options.

Certain skin conditions in women are linked to higher risks of metabolic syndrome and type 2 diabetes due to hormone imbalances.

The article suggests renaming Polycystic Ovarian Syndrome (PCOS) to "Hyperandrogenic Persistent Ovulatory Dysfunction Syndrome" (HA-PODS) for accuracy and consistency, but no final decision was made.

More high-quality research is needed to recommend flavonoids and saponins for clinical use.

Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.

Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.

Tiny particles called extracellular vesicles show promise for skin improvement and anti-aging in facial care but face challenges like low production and lack of research.

A protein called sFRP4 can slow down hair regrowth.