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The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Progesterone boosts alcohol's effect on brain, finasteride counters it.

COVID-19 may cause hair loss and scalp pain due to inflammation and changes in hair follicle receptors, but these symptoms typically resolve in 2 to 4 months.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Androgens can help prevent memory problems caused by apoE4.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

Testosterone may slow down wound healing and increase inflammation.

CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Finasteride may affect fetal brain development and increase arousal, but more research is needed for safety confirmation.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

A transwoman developed a brain tumor after nine years of hormone therapy, suggesting a possible link between the treatment and tumor development.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

SHBG binding properties are unchanged in male liver cirrhosis patients.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Diet changes can help reduce acne by limiting certain hormones.

Hair follicle bulge cells don't help skin regrow after glucocorticoid damage; interfollicular epidermis cells do.

Dutasteride does not impair mental function in elderly men with enlarged prostate.

High glucocorticoids cause pancreatic malfunction and malabsorption, reversible with enzyme supplements.