44 citations
,
November 2018 in “Journal of applied ecology” This review discusses the use of hair analysis for examining stress and reproduction hormone levels in wildlife and highlights the need for more comprehensive physiological validations across species.
42 citations
,
December 2019 in “Steroids” In this study, researchers developed a method to measure steroid hormones in hair and found that body hair typically contains higher levels of cortisone and testosterone compared to scalp hair, but hair pigmentation did not affect hormone concentrations significantly.
11 citations
,
October 2020 in “General and comparative endocrinology” This study found that age-related fluctuations in hormones and endocannabinoids in male C57BL/6 mice showed specific patterns, with peak values observed around 2.7 to 3.4 months, with these patterns seen in both plasma and hair but with different magnitudes.
4 citations
,
November 2024 in “The Journal of Steroid Biochemistry and Molecular Biology”
2 citations
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December 2020 in “Phytomedicine plus” In this study, researchers found that taking Saw palmetto and Pygeum africana supplements for five days altered the urinary steroid profile in a way that may interfere with the steroidal module of the Athlete Biological Passport.
30 citations
,
May 2015 in “Current Cardiology Reviews” This review analyzed observational studies on endogenous sex steroids and CVD risk, reporting mixed findings: lower testosterone and higher estradiol levels were associated with increased CVD risk, but significant literature gaps remain.
January 2020 in “Frontiers in Medical Case Reports” This case study reported that reducing glucocorticoids resolved calcinosis cutis in a dog with hypoadrenocorticism, while demodicosis was treated with a fluralaner chewable tablet.
23 citations
,
June 2019 in “Bioanalysis” This study found that monitoring endogenous steroid metabolites in serum may improve the detection of testosterone doping by highlighting promising biomarkers.
July 2023 in “The journal of sexual medicine” This study concluded that anabolic-androgenic steroids negatively impact male reproductive health, including reduced testosterone production, impaired sperm production, and increased risk of sexual dysfunction and metabolic issues.
March 2026 in “Lithuanian University of Health Sciences” In this case report, a rare instance of ACTH-independent hypercortisolism in a patient with long-standing Addison's disease led to the discovery of an adrenal cortical adenoma, successfully treated with adrenalectomy, underscoring the importance of considering functional adrenal tumors in such atypical biochemical scenarios.
This case study describes a 34-year-old male developing painful inflammatory scalp nodules post-scalp microinfusion of medication. The findings suggest that repeated microtrauma or bacterial colonization might trigger dissecting cellulitis in susceptible individuals, with exogenous testosterone as a potential modifier, not a direct cause.
July 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers found that both direct and witnessed trauma in mice were linked to lower levels of the neurosteroid allopregnanolone, and that boosting neurosteroidogenesis may alleviate PTSD-like symptoms, suggesting potential treatment strategies for PTSD stemming from either trauma type.
49 citations
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December 2017 in “Journal of pharmaceutical and biomedical analysis” This study developed and validated a high-resolution mass spectrometry method to screen for prohibited substances and analyze six endogenous steroids in urine according to World Antidoping Agency requirements, demonstrating its effectiveness for antidoping analysis.
November 2014 in “John Wiley & Sons, Ltd eBooks” This review discusses hormones that affect acne and highlights a statistically significant link between a low-glycemic-load diet and reduced acne activity, but reports no new experimental findings.
100 citations
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July 2004 in “The Journal of Sexual Medicine” This article reviews how various hormones may affect female sexual function and provides recommendations for diagnosing and treating endocrinologic sexual difficulties, but it reports no new clinical results.
72 citations
,
October 1998 in “Baillière's clinical endocrinology and metabolism” This article discusses the potential effects of exogenous testosterone, highlighting that its impact on prostate cancer progression, cardiovascular health, and behavior remains uncertain and needs further investigation.
January 2018 in “The Kaohsiung journal of medical sciences” This case report describes an atypical presentation of eruptive vellus hair cysts on the elbows, where standard diagnostic techniques were unreliable due to the loss of cystic structural integrity.
1 citations
,
October 2023 in “Journal of the Endocrine Society” In this case report, researchers highlight a 57-year-old HIV patient on ritonavir who developed Cushing’s syndrome from over-the-counter intranasal fluticasone, underscoring the risks of drug interactions and the importance of counseling patients about potential steroid ingredients in OTC products.
January 2023 in “Indian journal of pharmacy practice” This study observed that dermoscopic features of skin affected by topical corticosteroids and hydroquinone correlated with histopathological changes, highlighting the importance of awareness regarding their long-term adverse effects.
1 citations
,
January 2017 in “SAGE Open Medical Case Reports” This case report suggests that exacerbations of alopecia areata in a 40-year-old woman may be associated with sodium tetradecyl sulphate foam sclerotherapy treatments for varicose veins.
6 citations
,
August 2006 in “Journal of Cutaneous Pathology” This case report describes two brothers with an unusual, possibly treatment-resistant inflammatory variant of androgenic alopecia, featuring follicular isthmic lymphocytic inflammation and diffuse central scalp hair loss.
January 2023 in “Andrologia” This study found that American men undergoing fertility evaluation are older, more obese, and experience longer infertility durations than their Canadian counterparts, with potentially reversible factors being more prevalent in the US.
1 citations
,
November 2019 in “Archives of breast cancer” This review discusses non-oral hormonal contraceptives and other exogenous steroid hormones, reporting they are generally safe for temporary use in women without breast cancer, but data are limited.
81 citations
,
June 2006 in “Experimental Neurology” Neurosteroids may help prevent seizures in epilepsy.
4 citations
,
January 2018 in “General Physiology and Biophysics” In this study, finasteride-treated WAG/Rij rats showed a significant increase in spike-wave discharges when administered endogenous steroids THPROG and THDOC, indicating potential exacerbation of absence seizures.
34 citations
,
August 2015 in “Frontiers in Behavioral Neuroscience” This study found that augmenting or reducing allopregnanolone activity in the BNST affected contextual fear expression in rats, suggesting sex differences in anxiety may be linked to neuroactive steroid regulation.
1 citations
,
August 2024 in “Indian Dermatology Online Journal” In this case report, researchers observed that a female patient with severe hidradenitis suppurativa experienced complete resolution of her lesions after starting intramuscular exogenous testosterone as part of gender transition, suggesting its potential role in disease remission when other treatments were ineffective.
November 2022 in “Journal of the Endocrine Society” This case report describes a patient with ectopic Cushing's syndrome who experienced fatal complications from COVID-19, highlighting the challenges in managing such patients due to immune response alterations from endogenous hypercortisolemia.
7 citations
,
April 2022 in “Journal of pharmaceutical and biomedical analysis” This study describes a new method using high-resolution mass spectrometry for analyzing multiple steroids in human scalp hair, with newborn hair showing the highest steroid concentrations among examined age groups.
19 citations
,
June 2021 in “The world journal of men's health” This review examines the negative effects of anabolic-androgenic steroid use on the male reproductive system, including impaired testosterone production, sperm production issues, and adverse metabolic consequences without reporting new clinical results.