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TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Platelet-rich plasma can potentially promote hair growth by stimulating cell growth and increasing certain proteins.

New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

Spironolactone treatment increases the amount of testosterone available in the body.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Apoptosis is essential for human skin development and forming a functional epidermis.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Human skin can make serotonin and melatonin.

Wnt1/βcatenin signaling is crucial for heart repair after injury.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.

Fat cells help recruit healing cells and build skin structure during wound healing.

Understanding where cancer cells come from helps create better prevention and treatment methods.