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A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.

Estrogen affects how vitamin A is processed in mouse skin, which may impact acne treatment, hair growth, and skin defense.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Dutasteride may help protect neurons and reduce inflammation in Parkinson's disease.

Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

Mouse genital development depends on male or female hormones for specific features.

Managing side effects of endocrine therapy is crucial to improve adherence and survival in breast cancer patients.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

The document concludes that Functional Hypothalamic Amenorrhea should be carefully diagnosed and managed to prevent health complications, using lifestyle changes and specific medications.

The document concludes that managing health issues like menopause, cardiovascular risk, and hair loss is crucial for promoting longevity in aging women.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

Bisphenol-A (BPA) increases connections between brain cells and boosts their activity, but it blocks the effects of a male hormone on brain cell plasticity.

Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

PCOS is linked to a higher risk of endometrial cancer but not ovarian or breast cancer, and more research is needed on its role in cancer development and treatment effects.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Balding men had lower bone density, while balding women had higher hip bone density.

Environmental factors and chemicals might affect hormone balance and contribute to common hair loss.

Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.

Eating high-glycemic and dairy foods can increase hormones that may cause acne and other health issues.