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This review discusses nanotechnology-based therapies for chronic wound healing and highlights their potential, but it reports no new clinical results.

This study developed a carbohydrate chitosan-based biomaterial combined with a novel peptide to promote the chondrogenic differentiation of human adipose-derived stem cells, suggesting potential clinical applications for cartilage regeneration.

This review discusses recent advancements in nanotechnology-based treatments for chronic wound healing in diabetic models, noting that despite promising results, these innovations have yet to translate into widely available commercial products.

This review examines the potential of biomaterial-based wound dressings in managing diabetic foot ulcers, highlighting their versatility and therapeutic properties for promoting wound healing in individuals with diabetes mellitus.

This review examines integrins as pharmacological targets, discussing current integrin-based therapies and emphasizing the need to understand integrin mechanisms for successful drug development, without reporting new clinical results.

This review highlights that unresolved inflammation is a major issue in diabetic foot ulcers and discusses emerging biomaterials-based strategies to modulate the inflammatory response, potentially aiding in tissue regeneration and healing in these chronic wounds.

This review examines the potential mechanisms by which stem cell-derived cell-free therapy may prevent skin aging, highlighting various molecular targets and pathways involved in regeneration, oxidative stress regulation, ECM preservation, cell activity modulation, and inflammation.

This study highlights the critical role of mitochondria in skin aging and wound repair, suggesting that targeted interventions such as antioxidants, NAD⁺ boosters, and NRF2-based therapies may enhance mitochondrial function and improve cutaneous health.

In this study, researchers developed a microfluidics-based method to generate hair follicle germs on a large scale for potential hair regeneration therapies, demonstrating efficient hair follicle regeneration following transplantation into mice.

This review discusses recent advancements and ongoing challenges in engineering human skin with appendages using scaffold-free and scaffold-based bioengineering approaches, but it reports no new clinical results.

This review highlights that Trigonella foenum-graecum L. (fenugreek) shows promise as a versatile plant-based ingredient in cosmetics due to its phytochemicals, which offer benefits for skin and hair care, although further research is necessary for robust validation.

This study found that alkylation of kerateine cysteine residues created a cell-compatible method for controlling hydrogel erosion rates and therapeutic agent release in keratin-based systems.

This review highlights silk fibroin and its nanocomposites as promising materials for wound healing, addressing challenges in chronic wound treatment, especially in developing countries, and examines the obstacles in bringing silk-based products to market.

This narrative review synthesized current research on hormonal therapies in cosmetic dermatology, finding they offer promising, evidence-based applications for conditions like aging skin, acne, and melasma, but noting that safety and personalized treatment approaches are essential for responsible clinical use.

This study highlights that hydrogel formulations unexpectedly prolonged healing in trials, pointing to a need for design based on detailed pathophysiological insights rather than empirical methods, and suggests technologies like AI materials optimization and 3D bioprinting to aid their clinical use for cancer survivors.

In this study, researchers used two dermal papilla spheroid models to investigate hair cycle regression mechanisms and found that the vascular system enhances tissue physiology and gene modulation, while Retinol-based treatments can partially recover tissue degeneration observed over an extended culture period.

This review article evaluates the effectiveness of autologous fat transplantation in regenerative medicine and rejuvenation, highlighting its biocompatibility and non-immunogenic properties as a facial filler, and notes the variable outcomes based on adipose tissue size.

This review discusses the roles of mesenchymal stem cells in wound healing, particularly their interactions with immune cells, and highlights the potential and current limitations of MSC-based therapies for tissue regeneration.

In this review, the authors summarized the potential therapeutic effects of metal ions in treating cardiovascular diseases, highlighting their roles in protecting cells, inducing angiogenesis, and adjusting ion channel functions, as well as discussing delivery strategies involving biomaterials.

This review highlights recent advancements in using nanotechnology for scar prevention and treatment, emphasizing the unique properties of nanomaterials in drug delivery and the challenges that remain in maximizing their potential for effective scar interventions.

This review highlights the potential of bioengineered dermal scaffolds in tissue engineering to enhance wound healing by mimicking the dermal structure and supporting cellular processes, while also discussing recent advancements and challenges in scaffold technology.

This review discusses the roles of distinct immune cell types in skin wound healing, highlighting findings from animal studies, but provides no new clinical results.

This manuscript explores the development and future potential of injectable biomimetic gels in biomedical applications, highlighting their promise in wound healing and tissue regeneration, while also acknowledging challenges like mechanical durability and scalable production still persist.

This review explores advancements in cytokine engineering for regenerative medicine, highlighting the development of modified cytokines with enhanced stability and tissue-targeting, potentially improving treatments for chronic wounds and fibrotic diseases by promoting tissue healing and minimizing inflammation, while adapting concepts from cancer immunotherapy.

This perspective review discusses the crucial role of the stem cell niche in influencing stem cell function and its potential as a target for developing new regenerative medicine strategies, but reports no new clinical results.

This review discusses the potential of extracellular vesicles as cell-free tools in tissue engineering and regenerative medicine, noting their emerging role in promoting tissue repair without the risk of host rejection.

In this review, researchers discuss how mitochondria-targeted biophysical priming of autologous biologics, through methods like photobiomodulation and ultrasound, can potentially enhance skin rejuvenation and wound repair by modulating mitochondrial function in skin cells.

This review discusses ongoing concerns and advancements in the use of gelatin as a biomaterial in tissue engineering, highlighting improved tissue mimicry through techniques like 3D bioprinting and suggesting a future focus on disease detection and diagnosis rather than treatment.

This review examines how biochemical and biophysical induction factors influence cell fate in tissue engineering and reports no new experimental results.

This review discusses recent findings on cellular antioxidant responses to oxidative stress and their implications for treating various human diseases but reports no new clinical results.