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The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

Women with polycystic ovary syndrome tend to have a longer anogenital distance.

The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.

Men, particularly those with hair loss, are more likely to get the virus, and those with prostate cancer may have milder symptoms. Testosterone's role in the disease is unclear, and the virus doesn't seem to harm male fertility. Women with PCOS might be at higher risk. More research is needed.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

The oral glucose tolerance test is effective in detecting abnormal glucose tolerance in Indian women with PCOS.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

5α-reductase inhibitors like finasteride may not be effective or safe for transgender individuals, and more research is needed.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

Prediabetes may be a risk factor for hair loss.

Androgen levels can increase at any age, affecting symptoms like acne, hair loss, and prostate size.

More PDCD4 is linked to obesity, insulin problems, and cell death in ovaries for those with polycystic ovary syndrome.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

A 71-year-old woman developed male-like features due to high testosterone levels caused by a benign ovarian tumor, which was successfully removed by surgery.

A man fainted and felt unwell after using a strong hair growth product, but got better when he stopped using it.

Women with PCOS are at high risk of glucose metabolism issues and heart diseases, especially if overweight, highlighting the need for early intervention.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Hormone therapy greatly improves the quality of life for adults seeking gender reaffirmation, but more research is needed in India.

The review concludes that more research is needed to better improve the health outcomes for people with Polycystic Ovarian Syndrome.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Possible endocrine disorders caused woman's hair loss and obesity in painting.

A man with testotoxicosis was fertile despite low FSH levels, suggesting high testosterone may allow sperm production without FSH.