Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

Activating the Eda/Edar pathway improves wound healing by enhancing hair follicle growth.

This study found that antisense oligonucleotides can significantly reduce androgen receptor expression in cultured human sebocytes and may offer new therapeutic possibilities for androgen-associated skin diseases.

In this study, inactivating the TAF4 subunit of transcription factor TFIID in mouse epidermis disrupted gene expression linked to skin and hair function, and increased tumor risk.

This article reviews guidelines for testosterone replacement therapy in late-onset hypogonadism, emphasizing the need for clear indications and appropriate testing before treatment, but provides no new research findings.

This study found that mackerel-derived fermented fish oil extract and its component DHA promote hair growth by activating anagen pathways in dermal papilla cells.

This study found that premature hair loss due to stress does not occur in NK-1 receptor knockout or mast cell deficient mice, suggesting a key role for neurokinin substance P and mast cell interaction in stress-related hair follicle changes.

This review discusses the adverse effects of 5α-reductase inhibitors, finasteride and dutasteride, on sexual, psychological, and vascular health, emphasizing the need for physicians to inform patients of these risks.

This review discusses current and emerging drug therapies for treating androgenetic alopecia and alopecia areata, and reports no clinical results; it highlights a need for improved and novel treatments.

This review examines the role of nuclear hormone receptors in skin wound repair processes and reports no new clinical results, highlighting the importance of their interaction with skin cells for effective healing.

In this study, topical application of fibroblast growth factors was found to promote hair growth by inducing and prolonging the anagen phase in telogenic C57BL/6 mice, suggesting potential as hair growth-promoting agents.

This review discusses the use of 5α-reductase inhibitors in treating benign prostatic hyperplasia, highlighting their long-term effectiveness and benefits when combined with α1-adrenergic antagonists; it reports no new clinical results.

Testosterone and dihydrotestosterone affect hair growth, and new techniques like the folliculogram help study it, but fully understanding hair growth is still complex.

This study observed that a longer anterior clitoral anogenital distance (AGDAC) is associated with polycystic ovary syndrome in adult Mediterranean women.

This review discusses the physiological basis, history, and current development of male hormonal contraception, highlighting its potential risks and benefits, but reports no new research findings.

This article discusses whether testosterone's metabolism to 5α-dihydrotestosterone is necessary for androgenic effects in the skin but reports no new experimental results.

This study described four cases of delayed diagnosis of Cushing’s syndrome, highlighting that increased clinical awareness and screening could reduce its associated morbidity and mortality.

This study found that Rumex japonicus Houtt. root extract promoted hair growth by enhancing cell proliferation and preventing apoptosis in human dermal papilla cells and HaCaT cells, as well as in a mouse model.

This study observed that deleting PTEN in mouse facial motoneurons enhanced peripheral axon regeneration but also led to physiological changes and potential hyperplasia in older mice.

This study found that Ficus carica extract enhanced fertility markers, including hormone levels and reproductive organ activity, in rats of both sexes, suggesting potential benefits for managing fertility issues.

In this study, researchers found an increase in daily physical activity during the COVID-19 pandemic among students, with a notable rise in leisure walking and transportation, but also increased weekday sedentary behavior in men.

In this study, human dermal papilla cells exposed to wasabi leaf extract showed changes in cytokine-related gene expression, which the authors suggest could help clarify the biological effects of wasabi.

This study identified a crucial Gli2-Serpinh1 regulatory axis that regulates fibroblast state transitions during skin wound healing, shedding light on fibroblast heterogeneity and suggesting potential precision regenerative therapies.

In this lecture, Dr. Anna Gorecka and Dr. Ewa Bieber discuss how social media has influenced the rise of cosmetic surgery and patient expectations, as well as its connection to self-esteem and body dysmorphic disorder. Results are not reported in this summary.

This article discusses various synthetic and herbal treatments for alopecia, noting limited effectiveness and associated side effects of synthetic options, and reports no new clinical results.

This article reviews the clinical and histological features of acanthosis nigricans and its associations with insulin resistance and other conditions, but highlights the need for more research on its classification, severity assessment, and treatment options.

This perspective suggests that browning agents may not directly enhance UCP1 expression in white adipose tissue but instead induce browning through increased heat loss, prompting thermogenesis to compensate.

This study found that reducing testosterone levels in male mice accelerates wound healing and decreases inflammation, suggesting a potential therapeutic target for improving wound repair in elderly males.

This article discusses the impact of estrogens on skin aging, highlighting the potential benefits and unresolved effectiveness of alternatives like phytoestrogens and selective estrogen receptor modulators; it reports no new clinical results.

In this study, researchers observed that hyperandrogenic PCOS patients exhibited distinct miRNA and TGFβ signaling gene expression patterns in granulosa cells, suggesting these factors may play a role in PCOS pathogenesis.

This review examines the role of retinoic acid synthesis in hair follicles and sebaceous glands, focusing on its localization and function during normal and disease states, but reports no new results.