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Four patients with a type of rickets and hair loss had different mutations in their vitamin D receptor gene, causing it to not work properly.

Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

TAF4 is important for skin cell growth and helps prevent skin cancer in mice.

Hormones significantly affect women's sexual function, and more research is needed to improve treatments for sexual dysfunction with minimal side effects.

A man with hypoparathyroidism had other health issues that led to a diagnosis of a rare autoimmune disorder, APS-1.

The 2023 guideline for PCOS suggests using updated diagnostic criteria, assessing related health risks, and recommends lifestyle changes and specific treatments for symptoms and fertility issues.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

For women with moderate to severe unwanted hair growth or acne, birth control pills are the first choice, with other medications like cyproterone, spironolactone, flutamide, or finasteride as alternatives, and permanent hair removal should be done with electrolysis or laser.

New genes and pathways are important for testosterone production and male sexual development.

Late diagnosis of congenital adrenal hyperplasia can greatly affect physical development, gender identity, and sexual health.

Too much androgen can cause hair loss; finasteride may help.

Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.

The treatment effectively reduced hair growth and was safe for patients with PCOS, but it needs better bleeding control.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

RU 58841 may treat acne, hair loss, and excessive hair growth.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.

Antiandrogen drugs can reduce PSA levels in women with excess hair, suggesting PSA is a sign of male hormone activity in women.

Postmenopausal women with hyperandrogenism didn't have better metabolic health even after their testosterone levels became normal.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

Small hormonal imbalances can cause significant health problems, so more sensitive testing for hormone-disrupting chemicals is needed.

Dihydrotestosterone changes some hormone-related gene expressions in rat pituitary glands but doesn't affect the estrous cycle.

Combining genetic and physical trait analysis improves diagnosis accuracy for monogenic diabetes.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Spironolactone most effective for hirsutism, but has side effects.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.

People who carry the 21-Hydroxylase Deficiency gene are not more likely to have excessive male hormone levels.