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The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

Some men with early hair loss may have a male version of PCOS, affecting hormones and increasing health risks.

Children with classic congenital adrenal hyperplasia have thicker heart fat and are at higher risk for heart problems and early atherosclerosis.

Knuckle Acanthosis Nigricans is common in Latin American youth and may indicate early insulin resistance, especially in those with normal weight.

The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.

A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.

Melatonin improved cashmere production in goats during the first cycle but had no lasting effects on the next cycle.

Greek women with classic PCOS are more likely to have metabolic syndrome and insulin resistance than those with newer PCOS types.

A specific thyroid hormone resistance mutation may be linked to different types of hair loss.

A young woman's symptoms suggested PCOS, but tests and surgery confirmed and treated a rare ovarian tumor, resolving her condition.

Women with congenital adrenal hyperplasia (CAH) have more sexual function issues than those with polycystic ovary syndrome (PCOS), but physical activity can improve sexual functioning in all women.

Children and adults with Cushing's disease show different symptoms and males have more severe cases; surgery outcomes can be predicted by certain factors.

A 63-year-old woman's male-like symptoms were caused by a rare testosterone-producing ovarian tumor, treated by removing her ovaries and fallopian tubes.

Two different mutations in the vitamin D receptor gene cause different symptoms and responses to treatment in Lebanese patients with hereditary rickets.

Insulin resistance is linked to larger thyroid volume in patients with polycystic ovary syndrome.

The girl's condition improved with treatment, showing no new autoimmune diseases and hair regrowth.

Women with a certain type of tumor had higher levels of pregnancy hormone and male hormones, which decreased after treatment.

Identifying nonclassic congenital adrenal hyperplasia and carriers of CYP21 mutations is challenging, and genetic counseling is recommended due to their prevalence.

Regulating certain sex hormones may help delay facial aging.

Women with nonclassical congenital adrenal hyperplasia may have a higher risk of fertility issues and miscarriages, and should get genetic counseling.

The study suggests that hypothyroidism may cause alopecia areata.

A new gene mutation causes insulin resistance in a girl and her mother.

Hyperandrogenism increases heart disease risk in premenopausal women, but this risk is linked to obesity in postmenopausal women.

Effective PCOS treatments require targeting specific signaling pathways.

Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.

Ashwagandha root improved symptoms of nonclassic 11-hydroxylase deficiency in an elderly woman.

The conclusion is that thorough investigation of hypertension and hormonal dysfunctions is important, and there may be a link between these conditions and cancer.

Hairless protein can block vitamin D activation in skin cells.

Spironolactone may help reduce hair growth and testosterone levels in some women with hirsutism.

Brothers of women with PCOS tend to have higher levels of a hormone called DHEAS, indicating a possible genetic link.