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Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Some ovarian tumors can cause masculinization, and it's important to check for various causes when this symptom is present.

Zinc is effective for treating various skin conditions, including warts and acne.

Hair loss in men treated best with early medication or transplant, new treatments researched.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.

Many skin patients also have mental health issues, and doctors should treat both together.

Puberty often causes skin issues like acne and excessive sweating, and treatments require patience as results may vary.

Men with advanced liver disease and high oestrone and low testosterone levels have worse health outcomes.

The document concludes that transplantology has evolved with improved techniques and materials, making transplants more successful and expanding the types of transplants possible.

Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.

The document explains how male reproductive hormones work and affect the body.

Vitamin D deficiency is linked to a higher chance of metabolic syndrome in women with PCOS.

Hormone therapy increases the risk of heart-related issues in transgender women and may affect heart health in transgender men.

Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.

PCOS is common among Chinese women of reproductive age and linked to serious metabolic and reproductive issues, especially in obese women.

Hormones and genetics affect hair growth and patterns, with some changes reversible and others not.

The document concludes that accurate diagnosis and management of PCOS are crucial due to its associated health risks.

The document concludes that PCOS in adolescents is complex and requires comprehensive care to manage its symptoms and associated health risks.

The 18-year-old girl likely has a condition called müllerian agenesis, which caused her to not have a uterus and experience no menstrual periods.

Late diagnosis of congenital adrenal hyperplasia can greatly affect physical development, gender identity, and sexual health.

Diagnosing PCOS is challenging due to its complex and varied symptoms.

A girl with Denys-Drash syndrome was misdiagnosed due to biotin affecting her hormone test results.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

Women with PCOS often have irregular periods, a higher chance of infertility and miscarriages, and may improve fertility with lifestyle changes and treatment.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.

Skin doctors should know about skin and kidney disease links to prevent serious kidney problems.

MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.