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Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

The document concludes that oral finasteride and topical minoxidil are effective for genetic hair loss, while other treatments for different types of hair loss show promise but need more research.

Certain genetic variants increase the risk of resistance to hormone therapy in prostate cancer patients.

New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

There is no significant link between insulin resistance and certain hair disorders like idiopathic hirsutism and androgenic alopecia.

Resistance training improved BMI and menstrual regularity more in women with PCOS than aerobic training.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

Deleting the Trf1 protein in mice is safe and may help prevent cancer without major side effects.

Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.

Insulin resistance is a complex condition that can lead to many diseases and has few treatment options.

Environmental factors and chemicals might affect hormone balance and contribute to common hair loss.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.

Certain gene variations in AKT2 are more common in women with PCOS and are linked to higher levels of specific hormones and symptoms.

Vitamin D is important for skin health, but more research is needed to understand its full effects and treatment potential.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

To diagnose Polycystic Ovarian Syndrome, two out of three signs—irregular periods, high male hormone levels, or cysts on the ovaries—are needed.

Skin health and diseases are closely linked to metabolic processes.

The document says PCOS is a common hormonal disorder in women, diagnosed by certain criteria, and managed with lifestyle changes and various medications.

Doctors should recognize and treat PCOS early in primary care to manage symptoms and lower risk of other health issues.

PCOS is a common hormonal disorder in women, marked by symptoms like hair growth and menstrual issues, and requires personalized treatment.

Abusing steroids can damage your heart, muscles, reproductive system, liver, skin, and brain, and may increase the risk of Alzheimer's disease.

A new mutation linked to partial Androgen Insensitivity Syndrome and prostate cancer was found in a patient unhappy with their female gender assignment.

Understanding the mouse hair cycle is crucial for cancer research.

The document concludes that managing PCOS involves treating symptoms, regulating periods, and reducing health risks, with specific medications for fertility and metabolic issues.

Excessive hair growth in women, often from high androgen levels, is usually caused by PCOS, and can be treated with hair removal, medication, and possibly weight loss.

Lower SHBG levels may increase the risk of PCOS.

Hirsutism in women is often due to hormone sensitivity and has significant psychological effects.