This study found that while parabens in haircare products were within legal limits, all samples contained dibutyl phthalate, raising concerns about chronic exposure to endocrine disruptors.
February 2025 in “Endocrine Reviews” In this review, the authors explored how various hormones, particularly IGF-1, GH, estrogens, retinoids, and melatonin, influence human skin aging, highlighting potential new avenues for anti-aging therapies beyond the currently utilized topical retinoids and estrogens.
January 2025 in “Open Science Framework” The project aims to validate a nutritional intervention targeting the Redox–NO–Androgen Axis to restore mitochondrial, endothelial, and hormonal balance in male health disorders related to oxidative stress.
November 2024 in “Neliti” This review discusses the difficulty of diagnosing hypothyroidism due to its diverse, nonspecific symptoms that can vary greatly among patients and often mimic other conditions, which may require healthcare providers to be vigilant across various specialties to recognize and diagnose the condition effectively.
September 2024 in “Journal of the American Academy of Dermatology” This review discusses the limited evidence on the efficacy of platelet-rich plasma for treating endocrine therapy-induced and permanent chemotherapy-induced alopecia and reports no new clinical results.
June 2024 in “Ecotoxicology and Environmental Safety” This study observed that chronic and acute exposure to finasteride negatively impacted development, reproduction, and gene expression in Daphnia magna, highlighting the environmental risks of this pharmaceutical for freshwater ecosystems.
This study assessed the environmental impact of the drug finasteride on Daphnia magna, finding that both acute and chronic exposure impaired development and reproduction, affected gene expression and metabolism, and altered lipid profiles, highlighting the need to understand pharmaceutical impacts on aquatic ecosystems.
January 2021 in “Revista Dermatológica Centro Uraga” This review emphasizes the importance of endocrinologic evaluation in acne patients due to its association with endocrine disorders like hyperandrogenism; it reports no new clinical results.
May 2015 in “Journal of the American Academy of Dermatology” Certain drugs and supplements may contribute to hair loss in the frontal hairline in older women.
February 2013 in “Journal of The American Academy of Dermatology” Hair loss is a common, often overlooked side effect of hormone treatments for breast and prostate cancer.
August 2004 in “Veterinary Dermatology” This case report describes a 9‐year‐old red panda with progressive hair loss linked to bilateral granulosa cell tumors, suggesting an underlying endocrine abnormality.
September 2024 in “Journal of Investigative Dermatology” This study developed a deep learning-based tool to quantify individual hair fibers in mice, revealing distinct hair phenotypes linked to hormonal, genetic, and age-related factors, and suggesting its potential for new diagnostic methods through hair analysis.
April 2023 in “Clinical Chemistry and Laboratory Medicine” The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.
January 2018 in “Elsevier eBooks” This article discusses the hypothalamus-pituitary-testis axis in androgen production and spermatogenesis but presents no new research findings.
September 2009 in “Dermato-endocrinology” This summary discusses the role of endocrinology and nutrition in skin health, highlighting the importance of a balanced approach to UV exposure, nutrition, and potential benefits of probiotics without reporting new research findings.
December 1997 in “Journal of The European Academy of Dermatology and Venereology” In this study, hormonal abnormalities were detected in all investigated hirsute Saudi women, with elevated major androgens in 85.9% and polycystic ovaries in 59% of cases.
March 2023 in “JAAD case reports” This paper outlines that treatments reducing estrogen for estrogen receptor-positive breast cancer, such as SERMs and AIs, significantly improve life expectancy but may lead to alopecia in 15% to 25% of patients.
October 2022 in “International Journal of Research in Dermatology” This study suggests that hormonal disturbances play a role in female pattern hair loss and that trichoscopy may be a useful tool for diagnosis and differentiation from other conditions.
January 2011 in “Journal of biological research” This review discusses potential links between early-onset androgenetic alopecia and exposure to endocrine disruptors in adolescents, but reports no clinical results; the authors suggest further investigation.
This study found that in female androgenetic alopecia, androgen receptors are highly positive in affected areas, supporting their role as regulators of genetically predisposed hair follicles despite normal serum hormone levels.
20 citations
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January 2019 in “Frontiers of Hormone Research” This paper reviews the endocrinological aspects of hirsutism, focusing on the role of androgens in excessive hair growth and the related disorders, without presenting new findings.
4 citations
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December 2002 in “Gynecological Endocrinology” This review discusses the role of ovarian steroids in skin and hair metabolism, and suggests estrogens could slow skin aging post-menopause, while minoxidil is effective for women's hair loss.
December 1990 in “PubMed” This article discusses the role of androgens in causing hirsutism and male pattern baldness in women and emphasizes the need for antiandrogen treatment to manage these conditions, without reporting new clinical results.
1265 citations
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October 2013 in “The Journal of Clinical Endocrinology and Metabolism” This guideline from the Endocrine Society recommends using the Rotterdam criteria for diagnosing polycystic ovary syndrome and outlines first-line treatments, emphasizing hormonal contraceptives and lifestyle intervention.
75 citations
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September 2009 in “Dermato-endocrinology” This review discusses the skin's role in producing hormones and related substances, highlighting their potential in homeostasis and disease management, and reports no new clinical findings.
60 citations
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February 2010 in “Gynecological Endocrinology” This study suggests that adding metformin to diet and exercise improves insulin resistance and hyperandrogenism in women with PCOS, though lifestyle changes alone may enhance menstrual cycles.
43 citations
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October 2005 in “Molecular and cellular endocrinology” This review discusses how the CRH/POMC systems may regulate human hair follicle pigmentation and highlights the concept of "self-similarity" in melanocortin systems at both local and systemic levels, without presenting new experimental results.
42 citations
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March 2008 in “Molecular and Cellular Endocrinology” This review explores the potential (neuro-)endocrine influences on hair follicle epithelial stem cell biology and emphasizes the need for more systematic research, but it provides no new empirical results.
39 citations
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November 2021 in “Clinical Endocrinology” This review discusses a new multidisciplinary guideline for treating male hypogonadism and emphasizes a comprehensive approach but reports no new experimental results.
34 citations
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September 2020 in “BMC Endocrine Disorders” This review highlights that while dexamethasone may reduce mortality in severe COVID-19, no other drugs have proven effectiveness for treatment, emphasizing the need for clinical trials of existing medications.