January 2026 in “Frontiers in Oncology” This case report highlights that in postmenopausal women with severe hyperandrogenism, thorough adrenal and pelvic evaluations, hormonal profiling, and permanent pathology are essential for accurate diagnosis and management of androgen-secreting tumors, such as AGCTs, to prevent misdiagnosis and ensure effective treatment.
In this case study, a 12-month-old girl presenting with apyretic seizure and congenital alopecia was diagnosed with hereditary vitamin D-resistant rickets, highlighting the importance of comprehensive evaluation for accurate diagnosis.
September 2023 in “Biology of reproduction” This study suggests that the testosterone analogs 7α-Methyltestosterone and 7α-Ethyltestosterone may offer promising androgenic, progestogenic, and anabolic properties for development as male contraceptives.
This case report describes a 40-year-old man with four autoimmune diseases leading to MAS, and suggests an additional classification category for MAS including autoimmune hypothyroidism, alopecia universalis, celiac disease, and immune thrombocytopenic purpura.
January 2017 in “Springer eBooks” Over 40% of postmenopausal women experience hair loss, with treatments aiming to stop further loss and possibly thicken hair.
September 2014 in “Springer eBooks” This review discusses the evaluation and management of breast pain, or mastalgia, highlighting non-pharmacologic therapies and the limited role of surgical interventions, but reports no new clinical findings.
June 2025 in “Mağallaẗ ʻulūm al-rāfidayn” This study found that certain pyrazole derivatives may serve as effective 5α-reductase inhibitors with potential use in the treatment of androgenetic alopecia, based on molecular docking analyses.
10 citations
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September 2020 in “Metabolites” This study found that metabolite levels in hair samples differ significantly by hair color and segment, leading to recommendations for best practices in hair metabolomic studies.
4 citations
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September 2014 in “Elsevier eBooks” This review discusses the safety of dermatological medications used during pregnancy, highlighting that retinoids have strong teratogenic risks and should be used with caution; it reports no new clinical results.
1 citations
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May 2023 in “Journal of molecular evolution” This study explored the molecular biology of skin adaptations in pangolins, revealing that certain genes for lipid synthesis have inactive patterns, while others related to skin function remain intact, suggesting complex evolutionary changes in their skin physiology.
April 2026 in “International Journal of Research and Review” This article reviews current literature and suggests that managing gout with early urate-lowering therapy, within a 'treat-to-target' strategy, can help prevent systemic complications and address the rising prevalence of hyperuricemia-related diseases.
April 2024 in “Frontiers in medicine” This Delphi study found that moderate-to-severe alopecia areata in Poland, Czechia, Russia, and Türkiye significantly impacts quality of life and highlights an unmet need for more effective treatments.
This study aims to use a comprehensive health data set to develop a statistical model that can improve personalized and preventive health care by understanding relationships between various health parameters in individuals.
June 2022 in “International journal of research and review” This study highlights the increasing prevalence of hyperuricemia as a metabolic and vascular disorder due to lifestyle changes, emphasizing the need for early diagnosis of prehyperuricemia to prevent related non-communicable diseases and complications.
February 2026 in “Expert Review of Endocrinology & Metabolism” This review discusses the dermatologic manifestations and management of polycystic ovary syndrome, underscoring the need for mechanism-based, personalized treatments and integrated mental health support, but reports no new clinical results.
January 2020 in “Open Journal of Obstetrics and Gynecology” This study found that hirsutism, acne, acanthosis nigricans, and seborrheic dermatitis may serve as reliable cutaneous indicators of PCOS in women.
3 citations
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April 2020 in “Clinical endocrinology and metabolism journal” This review discusses imaging's role in the diagnosis and management of congenital adrenal hyperplasia and reports no new clinical results; it suggests a potential presentation route via incidental radiologic findings.
October 2024 in “Annals of Allergy Asthma & Immunology” This case study reports on a 4-year-old girl who developed telogen effluvium, a type of hair loss, after experiencing anaphylactic reactions to cow's milk. The authors highlight this as the first documentation of anaphylaxis potentially triggering telogen effluvium due to physiologic stress.
1 citations
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December 2022 in “Biomedicines” This study found that women diagnosed with PCOS who had hyperandrogenic symptoms at diagnosis were more likely to experience persistent androgenic symptoms and impaired quality of life in midlife.
July 2025 in “AACE Endocrinology and Diabetes” Ovarian hyperthecosis caused high testosterone and virilization symptoms in a 60-year-old woman, which improved after surgery.
This article discusses solitary hirsutism, emphasizing that treatment is mostly cosmetic unless contraception is also desired, and reports no new clinical results.
292 citations
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April 2024 in “Nature Reviews Disease Primers” Early diagnosis and treatment of PCOS are crucial to reduce health risks and costs.
2 citations
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October 2024 in “JCEM Case Reports” This study describes a case of a 35-year-old woman who developed symptoms of hyperandrogenism and disrupted steroidogenesis due to chronic use of electronic cigarettes containing compounds similar to etomidate, despite no genetic mutation indicating 11β-hydroxylase deficiency.
1 citations
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July 2022 in “BMC Women s Health” This report describes a rare case of elevated serum DHEAS levels in a postmenopausal woman, linked to an ovarian sex cord-stromal tumor rather than the adrenal glands, challenging common assumptions about androgen sources.
July 2025 in “Journal of Dermatology for Physician Assistants” This study by a panel of 13 clinicians led to 22 consensus statements recommending approaches for diagnosing scarring and nonscarring alopecias, suggesting scalp biopsy for suspected scarring alopecias and specific serologic tests for nonscarring types like alopecia areata based on clinical presentation.
August 2024 in “The Journal of Urology” This study updates guidelines for evaluating and managing male infertility, including revised testing recommendations for Y-chromosome microdeletions, use of pelvic MRI, and testicular sperm in nonazoospermic males.
May 2023 in “Frontiers in Endocrinology” This review article discusses recent updates on the skin manifestations associated with thyroid disease, emphasizing their role as early indicators of thyroid hormone dysregulation.
April 2023 in “Elsevier eBooks” This review summarizes the prevalence and range of health issues associated with polycystic ovary syndrome in North America but does not provide new clinical findings.
May 2022 in “Indian Journal of Pharmacology” This case report highlights a rare instance of valproate-induced hypertensive urgency in a 2-year-old girl, with improvement after stopping the medication.
49 citations
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December 2007 in “Fertility and Sterility” This case report describes two infertile patients who experienced significant improvements in sperm concentrations six months after stopping finasteride.