24 citations
,
January 2010 in “Annales d'endocrinologie” This review discusses treatment options for hirsutism in women of childbearing age, focusing on the use of contraceptives, CPA, spironolactone, and third-line therapies, and reports no clinical results.
22 citations
,
August 2011 in “Endocrine Practice” This review discusses the etiology, diagnosis, and management strategies for hirsutism, noting that serious underlying disorders are rare and emphasizing targeted treatment to manage testosterone's effects.
14 citations
,
January 2012 in “Endocrine development” This article reviews the challenges in diagnosing mild hyperandrogenism in adolescent girls, discussing potential causes like PCOS and treatment options, but reports no new clinical results.
14 citations
,
January 2000 in “Endocrine Journal” This case report documents a 57-year-old woman with a renin-producing adrenocortical carcinoma, revealing metastasis in the neck and providing insights into treatment effectiveness with trilostane and mitotane.
November 2012 in “Endocrine Practice” This review outlines the physiological roles of 5a-reductases and highlights the need for further research to better understand their function and minimize adverse effects from their inhibitors used in treatment.
116 citations
,
December 2017 in “International Journal of Women's Dermatology” This review discusses various treatment options for adult female acne, highlighting the need for tailored approaches due to individual patient needs and reports no clinical outcomes.
66 citations
,
September 2008 in “Dermatologic therapy” This review discusses medical treatments for hirsutism, focusing on oral contraceptives and other therapies, but reports no new results; the authors emphasize the lack of evidence for insulin sensitizers in treating hirsutism alone.
49 citations
,
June 1998 in “Journal of Endocrinological Investigation” In this study, both cyproterone acetate-estrogen combination (Diane®) and finasteride were effective in reducing hirsutism, but Diane® showed greater long-term efficacy and cost-effectiveness.
42 citations
,
January 2024 in “Frontiers in Endocrinology” This review discusses polycystic ovary syndrome treatments, focusing on the potential benefits and safety of herbs and phytochemicals, and reports no new clinical results.
34 citations
,
September 2020 in “BMC Endocrine Disorders” This review highlights that while dexamethasone may reduce mortality in severe COVID-19, no other drugs have proven effectiveness for treatment, emphasizing the need for clinical trials of existing medications.
20 citations
,
January 2016 in “Open Journal of Endocrine and Metabolic Diseases” This article discusses the prevalence, diagnosis, and treatment of polycystic ovary syndrome, emphasizing its early diagnosis and management due to potential reproductive and metabolic complications, but reports no new findings.
17 citations
,
October 2012 in “Dermatologic clinics” This article discusses diagnostic and treatment options for excessive hair growth in women, noting a need for holistic approaches to address associated psychological issues, but it does not present new clinical findings.
3 citations
,
May 2012 in “BMC Endocrine Disorders” This article presents a unique case of post-partum panhypopituitarism and autoimmune conditions in a 37-year-old woman from Africa, emphasizing the need for early diagnosis and treatment to improve outcomes in similar settings.
1 citations
,
January 2020 in “Elsevier eBooks” Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.
October 2024 in “Journal of the Endocrine Society” A woman experienced fluctuating thyroid conditions and eye disease, but her symptoms improved with treatment.
October 2023 in “BMC endocrine disorders” In this case study, researchers observed a 5.8-year-old male with peripheral precocious puberty due to a germ cell tumor, marked by elevated human chorionic gonadotropin levels. Treatment normalized hormone levels and arrested the puberty progression, highlighting melatonin's potential role in transitions to central precocious puberty.
January 2009 in “Elsevier eBooks” This chapter reviews botanical treatments for polycystic ovary syndrome, discussing potential benefits but presenting no new clinical results; it emphasizes the use of botanicals for managing symptoms like anovulation, insulin resistance, and inflammation.
October 2024 in “Journal of the Endocrine Society” This report describes varied causes of hirsutism in young females and highlights the need to revise diagnoses if initial treatments for common etiologies like PCOS do not yield results.
9 citations
,
January 1997 in “Gynecological Endocrinology” This review discusses the regulation of hair growth, causes of excessive androgen secretion, and current safe solutions for hyperandrogenism manifestations in women but reports no new clinical results.
18 citations
,
June 2010 in “Current medicinal chemistry” This review discusses current treatment options for hirsutism, emphasizing the importance of combining therapies for better outcomes, but reports no new clinical findings.
212 citations
,
September 2008 in “Journal of The American Academy of Dermatology” This review discusses the various treatment options for male and female pattern hair loss and provides no new clinical results; the authors outline the most effective strategies based on existing evidence.
183 citations
,
March 1982 in “JAMA” This study reported that spironolactone at 200 mg/day significantly improved facial hair growth in women with hirsutism and showed a sustained reduction in ovarian androgens over one year.
113 citations
,
April 1999 in “The Journal of Clinical Endocrinology and Metabolism” This study found that all four treatments—flutamide, finasteride, ketoconazole, and EE-CPA—significantly reduced hirsutism, but EE-CPA and flutamide appeared most effective, with varying effects on androgen levels and side-effect profiles.
105 citations
,
February 2011 in “The Journal of Clinical Endocrinology & Metabolism” Treating sleep apnea in young obese women with PCOS can improve heart health and insulin sensitivity.
28 citations
,
March 1942 in “Journal of Endocrinology” This article reviews studies on thyroid influence on hair growth, noting varied results, including accelerated growth in some normal and underfed rats after thyroid administration, but reports no clinical results.
19 citations
,
October 2012 in “Frontiers of Hormone Research” This article reviews treatment strategies for ovulation induction in women with PCOS seeking pregnancy, emphasizing lifestyle changes and pharmacological options, and reports no new clinical findings.
12 citations
,
August 2000 in “Fertility and Sterility” Topical finasteride doesn't reduce DHT levels, hinting at an endocrine role in hair loss.
11 citations
,
July 2003 in “The Nurse practitioner” This article reviews diagnostic and management strategies for polycystic ovary syndrome in primary care and reports no new clinical results; it also discusses when specialist referral is appropriate.
9 citations
,
March 2022 in “Journal of the Endocrine Society” This study found that testosterone more accurately predicts PCOS diagnosis than 11-oxyandrogens, which were linked with hirsutism severity and showed varying responses to contraceptive and metformin treatments.
9 citations
,
January 2016 in “Journal of cosmetology & trichology” This article reviews the characteristics and distribution of alopecia areata and reports no new clinical results.