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The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Antiandrogens are somewhat effective in reducing excessive hair growth in women.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.

The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.

Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Myo-inositol helps improve skin conditions and metabolic profiles in young women with PCOS.

Evaluate postmenopausal women with high androgen levels using medical history, physical exams, lab tests, and imaging to manage health risks.

Reduced AR gene methylation may cause early pubic hair growth in girls.

Mice with human gene experienced hair loss when treated with DHT.

The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.

Vitamin D3 analogs can promote hair growth in mice genetically prone to hair loss.

Intravaginal testosterone cream improves sexual satisfaction and reduces vaginal discomfort in postmenopausal women on breast cancer treatment without affecting hormone levels.

Treatment with a hormone agonist can reduce excess male hormones in postmenopausal women without surgery.