12 citations,
August 2000 in “Fertility and Sterility” Topical finasteride doesn't reduce DHT levels, hinting at an endocrine role in hair loss.
76 citations,
October 2016 in “Clinics in dermatology” Sex hormones, especially androgens, play a key role in causing acne.
15 citations,
January 2002 in “Gynecological endocrinology” Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.
220 citations,
August 1988 in “Clinical endocrinology” Melatonin may help with sleep issues, depression, and cancer, but more research is needed.
31 citations,
November 2020 in “International journal of molecular sciences” Adipokines affect skin health and could be targeted for treating skin diseases.
May 2023 in “Stem Cells International” Different parts of the body's fat tissue have unique cell types and characteristics, which could help treat chronic wounds.
23 citations,
July 2003 in “Pharmacology, Biochemistry and Behavior” Finasteride blocks progesterone's effect on absence seizures in rats.
29 citations,
April 2004 in “Annals of Pharmacotherapy” Finasteride reduces hirsutism effectively with fewer side effects but is a second-choice treatment due to safety concerns.
4 citations,
July 2021 in “Journal of Dermatological Treatment” Finasteride helps hair growth but may cause sexual side effects and depression.
23 citations,
January 2019 in “International Journal of Dermatology” Finasteride improves hair growth and reduces hirsutism in women, but side effects and optimal dosages need further research.
5 citations,
June 2012 in “Journal of Cosmetic and Laser Therapy” Finasteride and intense pulsed light effectively reduce unwanted facial hair in women, but may not be cost-effective.
5 citations,
July 2003 in “Drug Development Research” Fluridil promotes hair growth safely and effectively for androgenetic alopecia.
4 citations,
January 2015 in “Journal of drug assessment” Finasteride gel effectively and safely reduces hair thickness in women with excessive hair growth.
May 2024 in “Brazilian Journal of Hair Health” Finasteride-loaded nanoparticles were successfully created for potential improved hair growth treatment.
December 2023 in “Research in pharmacy” Phytotherapeutic compounds and supplements can help manage Polycystic Ovarian Syndrome (PCOS).
October 2020 in “Journal of Pharmaceutical Sciences” Topical finasteride with EGCG or TA improves drug release and dermal uptake, potentially treating hair loss effectively.
5 citations,
July 2017 in “International journal of endocrinology and metabolism/International journal of endocrinology and metabolism.” Two siblings with a genetic mutation had a form of rickets that doesn't respond to vitamin D.
January 2022 in “Springer eBooks” 1 citations,
October 2022 in “Springer eBooks” Testosterone is key for male sexual function, and treating hormone imbalances can improve sexual issues.
2 citations,
March 2021 in “Cutis” Some breast cancer treatments, like taxanes, can cause long-term hair loss.
54 citations,
March 2009 in “BioEssays” Hormones control keratin production in skin and hair.
97 citations,
September 2016 in “Reviews in Endocrine and Metabolic Disorders” The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.
October 2022 in “International Journal of Research in Dermatology” Hormonal imbalances contribute to female hair loss, and trichoscopy is a useful diagnostic tool.
8 citations,
January 2018 in “Science of the total environment” Australian fur seals' fur shows high levels of pollutants, which may be linked to hair loss in young female seals.
January 2022 in “IntechOpen eBooks” Some lesser-known causes of PCOS include autoimmune issues, genetic mutations, and changes in the body's microbiome.
22 citations,
November 2017 in “Scientific Reports” The pituitary gland functions normally even after losing most SOX2+ stem cells.
1265 citations,
October 2013 in “The Journal of Clinical Endocrinology and Metabolism” The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.
11 citations,
July 2016 in “Endocrinology” Higher Lnk protein levels in ovaries may lead to insulin resistance in women with PCOS.
284 citations,
February 2008 in “Pediatrics” Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.
103 citations,
June 2018 in “International Journal of Molecular Sciences” FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.