1533 citations,
October 2008 in “Endocrine reviews” Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
277 citations,
July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
224 citations,
March 2006 in “Seminars in Cutaneous Medicine and Surgery” The document concludes that understanding hair follicle biology can lead to better hair loss treatments.
165 citations,
December 2002 in “Molecular and Cellular Endocrinology” Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.
127 citations,
December 2007 in “Journal of Investigative Dermatology” Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.
103 citations,
June 2007 in “Endocrinology and Metabolism Clinics of North America” Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.
103 citations,
October 2003 in “Birth Defects Research” Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.
77 citations,
March 2001 in “Clinics in Dermatology” Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.
76 citations,
November 2009 in “Medical Clinics of North America” Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.
76 citations,
September 1992 in “Endocrinology” The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.
70 citations,
April 2013 in “Endocrine” Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.
53 citations,
February 2022 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” AMH helps estimate ovarian reserve but doesn't predict pregnancy chances; age is more important.
53 citations,
October 1984 in “Endocrine reviews” Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.
49 citations,
June 2009 in “Seminars in Cutaneous Medicine and Surgery” The cosmetic industry should adapt to the varied beauty standards of ethnic groups and offer specialized treatments.
43 citations,
September 2012 in “International Journal of Dermatology” Hormonal therapies are safe and effective for treating adult women's acne.
39 citations,
September 2011 in “Tissue Engineering Part B-reviews” Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.
38 citations,
February 2005 in “The journal of sexual medicine” The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.
37 citations,
June 2021 in “Journal of the European Academy of Dermatology and Venereology” Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.
31 citations,
October 2005 in “British Journal of Dermatology” Hair loss in women not always linked to increased oil production; other factors may be involved.
30 citations,
March 2001 in “Environmental Health Perspectives” Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.
27 citations,
July 2012 in “Dermatologic Surgery” Higher caspase-1 levels found in balding scalps; reducing it may help treat hair loss.
26 citations,
January 2013 in “BioMed Research International” Hormonal changes after childbirth and menopause can lead to women's hair loss and facial hair growth, with a need for better treatments.
18 citations,
May 2016 in “Annals of Medicine” The article concludes that correctly diagnosing systemic causes of hair loss requires a detailed clinical evaluation and a systematic diagnostic approach.
18 citations,
March 2009 in “Medical Hypotheses” The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.
18 citations,
June 1988 in “Culture, medicine and psychiatry” The perception of excessive hair growth in women as abnormal is more influenced by cultural norms than by medical reasons.
15 citations,
September 1984 in “Veterinary Clinics of North America: Small Animal Practice” The document explains various skin conditions in cats and how to diagnose and treat them.
14 citations,
September 2019 in “Eye” Some oral medications may help treat central serous chorioretinopathy, especially eplerenone, but more research is needed.
11 citations,
February 2003 in “Baillière's best practice & research. Clinical obstetrics & gynaecology/Baillière's best practice and research in clinical obstetrics and gynaecology” Acne and increased body hair in teenage girls are normal but severe cases may need hormone evaluation and treatment can prevent diabetes linked to PCO.
10 citations,
April 2016 in “Research and reports in transdermal drug delivery” Transfollicular drug delivery is promising but needs more research to improve and understand it better.
9 citations,
March 2001 in “Clinics in dermatology” Hirsutism in women is often due to hormone sensitivity and has significant psychological effects.