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Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.

Removing part of the vitamin D receptor stops vitamin D from working properly.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Fat cells help recruit healing cells and build skin structure during wound healing.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.

Oestrogens are key for bone growth during puberty in both boys and girls.

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.

Hair loss causes stress and affects mental health; treatment and support needed.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

Lowering testosterone speeds up wound healing in male mice.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.